8/26/2017 | Portland State | 6 | at | BYU | 20 | | | |
| Oregon State | 27 | at | Colorado State | 58 | | | |
| Hawaii | 38 | at | Massachusetts | 35 | | | |
| Stanford | 62 | vs | Rice | 7 | | Sydney AU | |
| South Florida | 42 | at | San Jose State | 22 | | | |
8/31/2017 | New Mexico State | 31 | at | Arizona State | 37 | | | |
| Florida A&M | 7 | vs | Arkansas | 49 | | Little Rock AR | |
| Florida Intl | 17 | at | UCF | 61 | | | |
| Rhode Island | 27 | at | Central Michigan | 30 | 3OT | | |
| Austin Peay | 14 | at | Cincinnati | 26 | | | |
| Holy Cross | 20 | at | Connecticut | 27 | | | |
| Tennessee State | 17 | at | Georgia State | 10 | | | |
| Sacramento State | 6 | at | Idaho | 28 | | | |
| Ohio State | 49 | at | Indiana | 21 | | | |
| UL Monroe | 29 | at | Memphis | 37 | | | |
| Buffalo | 7 | at | Minnesota | 17 | | | |
| Tulsa | 24 | at | Oklahoma State | 59 | | | |
| Elon | 13 | at | Toledo | 47 | | | |
| North Dakota | 16 | at | Utah | 37 | | | |
| Presbyterian | 7 | at | Wake Forest | 51 | | | |
9/1/2017 | Fordham | 6 | at | Army | 64 | | | |
| Colorado State | 3 | vs | Colorado | 17 | | Denver CO | |
| UNC-Charlotte | 7 | at | Eastern Michigan | 24 | | | |
| Navy | 42 | at | Florida Atlantic | 19 | | | |
| Boston College | 23 | at | Northern Illinois | 20 | | | |
| Washington | 30 | at | Rutgers | 14 | | | |
| Central Conn | 7 | at | Syracuse | 50 | | | |
| Utah State | 10 | at | Wisconsin | 59 | | | |
9/2/2017 | VMI | 0 | at | Air Force | 62 | | | |
| Florida State | 7 | vs | Alabama | 24 | | Atlanta GA | |
| Alabama A&M | 7 | at | UAB | 38 | | | |
| Northern Arizona | 24 | at | Arizona | 62 | | | |
| Georgia Southern | 7 | at | Auburn | 41 | | | |
| Liberty | 48 | at | Baylor | 45 | | | |
| Troy | 13 | at | Boise State | 24 | | | |
| Kent State | 3 | at | Clemson | 56 | | | |
| Massachusetts | 28 | at | Coastal Carolina | 38 | | | |
| North Carolina Central | 7 | at | Duke | 60 | | | |
| James Madison | 34 | at | East Carolina | 14 | | | |
| Michigan | 33 | vs | Florida | 17 | | Arlington TX | |
| Incarnate Word | 0 | at | Fresno State | 66 | | | |
| Appalachian State | 10 | at | Georgia | 31 | | | |
| Western Carolina | 18 | at | Hawaii | 41 | | | |
| Ball State | 21 | at | Illinois | 24 | | | |
| Wyoming | 3 | at | Iowa | 24 | | | |
| Northern Iowa | 24 | at | Iowa State | 42 | | | |
| SE Missouri State | 16 | at | Kansas | 38 | | | |
| Central Arkansas | 19 | at | Kansas State | 55 | | | |
| Northwestern State | 24 | at | Louisiana Tech | 52 | | | |
| Southeastern Louisiana | 48 | at | UL Lafayette | 51 | | | |
| BYU | 0 | vs | LSU | 27 | | New Orleans LA | |
| Miami-Ohio | 26 | at | Marshall | 31 | | | |
| Bethune-Cookman | 13 | at | Miami-Florida | 41 | | | |
| Bowling Green | 10 | at | Michigan State | 35 | | | |
| Vanderbilt | 28 | at | Middle Tenn State | 6 | | | |
| South Alabama | 27 | at | Mississippi | 47 | | | |
| Charleston Southern | 0 | at | Mississippi State | 49 | | | |
| Missouri State | 43 | at | Missouri | 72 | | | |
| Arkansas State | 36 | at | Nebraska | 43 | | | |
| Abilene Christian | 14 | at | New Mexico | 38 | | | |
| California | 35 | at | North Carolina | 30 | | | |
| Lamar | 14 | at | North Texas | 59 | | | |
| Nevada | 20 | at | Northwestern | 31 | | | |
| Temple | 16 | at | Notre Dame | 49 | | | |
| Hampton | 0 | at | Ohio | 59 | | | |
| UTEP | 7 | at | Oklahoma | 56 | | | |
| Albany NY | 17 | at | Old Dominion | 31 | | | |
| Southern Utah | 21 | at | Oregon | 77 | | | |
| Portland State | 32 | at | Oregon State | 35 | | | |
| Akron | 0 | at | Penn State | 52 | | | |
| Youngstown State | 21 | at | Pittsburgh | 28 | OT | | |
| Louisville | 35 | vs | Purdue | 28 | | Indianapolis IN | |
| UC Davis | 17 | at | San Diego State | 38 | | | |
| Cal Poly | 13 | at | San Jose State | 34 | | | |
| Stephen F. Austin | 14 | at | SMU | 58 | | | |
| North Carolina State | 28 | vs | South Carolina | 35 | | Charlotte NC | |
| Stony Brook | 17 | at | South Florida | 31 | | | |
| Western Michigan | 31 | at | Southern California | 49 | | | |
| Kentucky | 24 | at | Southern Miss | 17 | | | |
| Jackson State | 0 | at | TCU | 63 | | | |
| Maryland | 51 | at | Texas | 41 | | | |
| Houston Baptist | 11 | at | Texas State | 20 | | | |
| Eastern Washington | 10 | at | Texas Tech | 56 | | | |
| Houston | | at | Texas-San Antonio | | | Postponed | |
| Grambling | 14 | at | Tulane | 43 | | | |
| Howard | 43 | at | UNLV | 40 | | | |
| William & Mary | 10 | at | Virginia | 28 | | | |
| Montana State | 0 | at | Washington State | 31 | | | |
| Eastern Kentucky | 17 | at | Western Kentucky | 31 | | | |
9/3/2017 | Texas A&M | 44 | at | UCLA | 45 | | | |
| West Virginia | 24 | vs | Virginia Tech | 31 | | Landover MD | |
9/4/2017 | Tennessee | 42 | at | Georgia Tech | 41 | 2OT | | |
9/7/2017 | Idaho State | 13 | at | Utah State | 51 | | | |
9/8/2017 | Memphis | | at | UCF | | | Cancelled WX | |
| Alcorn State | 10 | vs | Florida Intl | 17 | | Birmingham AL | |
| Ohio | 21 | at | Purdue | 44 | | | |
| Oklahoma State | 44 | at | South Alabama | 7 | | | |
9/9/2017 | Ark Pine Bluff | 3 | at | Akron | 52 | | | |
| Fresno State | 10 | at | Alabama | 41 | | | |
| Savannah State | 7 | at | Appalachian State | 54 | | | |
| Houston | 19 | at | Arizona | 16 | | | |
| San Diego State | 30 | at | Arizona State | 20 | | | |
| TCU | 28 | at | Arkansas | 7 | | | |
| Miami-Florida | | vs | Arkansas State | | | Cancelled WX | |
| Buffalo | 17 | at | Army | 21 | | | |
| UAB | 31 | at | Ball State | 51 | | | |
| Texas-San Antonio | 17 | at | Baylor | 10 | | | |
| Wake Forest | 34 | at | Boston College | 10 | | | |
| South Dakota | 35 | at | Bowling Green | 27 | | | |
| Utah | 19 | at | BYU | 13 | | | |
| Weber State | 20 | at | California | 33 | | | |
| Auburn | 6 | at | Clemson | 14 | | | |
| Texas State | 3 | at | Colorado | 37 | | | |
| Abilene Christian | 10 | at | Colorado State | 38 | | | |
| South Florida | | at | Connecticut | | | Cancelled WX | |
| Northwestern | 17 | at | Duke | 41 | | | |
| Northern Colorado | | at | Florida | | | Cancelled WX | |
| UL Monroe | | at | Florida State | | | Cancelled WX | |
| New Hampshire | 22 | at | Georgia Southern | 12 | | | |
| Jacksonville State | 10 | at | Georgia Tech | 37 | | | |
| UNLV | 44 | at | Idaho | 16 | | | |
| Western Kentucky | 7 | at | Illinois | 20 | | | |
| Iowa | 44 | at | Iowa State | 41 | OT | | |
| Central Michigan | 45 | at | Kansas | 27 | | | |
| UNC-Charlotte | 7 | at | Kansas State | 55 | | | |
| Howard | 31 | at | Kent State | 38 | | | |
| Eastern Kentucky | 16 | at | Kentucky | 27 | | | |
| Mississippi State | 57 | at | Louisiana Tech | 21 | | | |
| Chattanooga | 10 | at | LSU | 45 | | | |
| Towson | 17 | at | Maryland | 63 | | | |
| Old Dominion | 17 | at | Massachusetts | 7 | | | |
| Austin Peay | 10 | at | Miami-Ohio | 31 | | | |
| Cincinnati | 14 | at | Michigan | 36 | | | |
| Western Michigan | 14 | at | Michigan State | 28 | | | |
| Tennessee-Martin | 23 | at | Mississippi | 45 | | | |
| South Carolina | 31 | at | Missouri | 13 | | | |
| Tulane | 21 | at | Navy | 23 | | | |
| Toledo | 37 | at | Nevada | 24 | | | |
| New Mexico State | 30 | at | New Mexico | 28 | | | |
| Louisville | 47 | at | North Carolina | 35 | | | |
| Marshall | 20 | at | North Carolina State | 37 | | | |
| Eastern Illinois | 10 | at | Northern Illinois | 38 | | | |
| Georgia | 20 | at | Notre Dame | 19 | | | |
| Oklahoma | 31 | at | Ohio State | 16 | | | |
| Nebraska | 35 | at | Oregon | 42 | | | |
| Minnesota | 48 | at | Oregon State | 14 | | | |
| Pittsburgh | 14 | at | Penn State | 33 | | | |
| Eastern Michigan | 16 | at | Rutgers | 13 | | | |
| North Texas | 32 | at | SMU | 54 | | | |
| Stanford | 24 | at | Southern California | 42 | | | |
| Southern | 0 | at | Southern Miss | 45 | | | |
| Middle Tenn State | 30 | at | Syracuse | 23 | | | |
| Villanova | 13 | at | Temple | 16 | | | |
| Indiana State | 7 | at | Tennessee | 42 | | | |
| San Jose State | 0 | at | Texas | 56 | | | |
| Nicholls State | 14 | at | Texas A&M | 24 | | | |
| Alabama State | 7 | at | Troy | 34 | | | |
| UL Lafayette | 42 | at | Tulsa | 66 | | | |
| Hawaii | 23 | at | UCLA | 56 | | | |
| Rice | 31 | at | UTEP | 14 | | | |
| Alabama A&M | 0 | at | Vanderbilt | 42 | | | |
| Indiana | 34 | at | Virginia | 17 | | | |
| Delaware | 0 | at | Virginia Tech | 27 | | | |
| Montana | 7 | at | Washington | 63 | | | |
| Boise State | 44 | at | Washington State | 47 | 3OT | | |
| East Carolina | 20 | at | West Virginia | 56 | | | |
| Florida Atlantic | 14 | at | Wisconsin | 31 | | | |
| Gardner-Webb | 0 | at | Wyoming | 27 | | | |
9/14/2017 | New Mexico | 14 | at | Boise State | 28 | | | |
9/15/2017 | Illinois | 23 | at | South Florida | 47 | | | |
| Massachusetts | 21 | at | Temple | 29 | | | |
| Arizona | 63 | at | UTEP | 16 | | | |
9/16/2017 | Iowa State | 41 | at | Akron | 14 | | | |
| Colorado State | 23 | at | Alabama | 41 | | | |
| Coastal Carolina | 23 | at | UAB | 30 | | | |
| Ark Pine Bluff | 3 | at | Arkansas State | 48 | | | |
| Mercer | 10 | at | Auburn | 24 | | | |
| Tennessee Tech | 13 | at | Ball State | 28 | | | |
| Notre Dame | 49 | at | Boston College | 20 | | | |
| Wisconsin | 40 | at | BYU | 6 | | | |
| Colgate | 10 | at | Buffalo | 33 | | | |
| Mississippi | 16 | at | California | 27 | | | |
| Georgia Tech | | vs | UCF | | | Cancelled WX | |
| Northern Colorado | 21 | at | Colorado | 41 | | | |
| Baylor | 20 | at | Duke | 34 | | | |
| Virginia Tech | 64 | at | East Carolina | 17 | | | |
| Tennessee | 20 | at | Florida | 26 | | | |
| Bethune-Cookman | 0 | at | Florida Atlantic | 45 | | | |
| Samford | 14 | at | Georgia | 42 | | | |
| Rice | 3 | at | Houston | 38 | | | |
| Florida Intl | | vs | Indiana | | | Cancelled WX | |
| North Texas | 14 | at | Iowa | 31 | | | |
| Southern Miss | 28 | at | UL Monroe | 17 | | | |
| Clemson | 47 | at | Louisville | 21 | | | |
| Kent State | 0 | at | Marshall | 21 | | | |
| UCLA | 45 | at | Memphis | 48 | | | |
| Cincinnati | 21 | at | Miami-Ohio | 17 | | | |
| Air Force | 13 | at | Michigan | 29 | | | |
| Middle Tenn State | 3 | at | Minnesota | 34 | | | |
| LSU | 7 | at | Mississippi State | 37 | | | |
| Purdue | 35 | at | Missouri | 3 | | | |
| Northern Illinois | 21 | at | Nebraska | 17 | | | |
| Idaho State | 30 | at | Nevada | 28 | | | |
| Troy | 27 | at | New Mexico State | 24 | | | |
| Furman | 16 | at | North Carolina State | 49 | | | |
| Bowling Green | 7 | at | Northwestern | 49 | | | |
| Army | 7 | at | Ohio State | 38 | | | |
| Kansas | 30 | at | Ohio | 42 | | | |
| Tulane | 14 | at | Oklahoma | 56 | | | |
| North Carolina | 53 | at | Old Dominion | 23 | | | |
| Georgia State | 0 | at | Penn State | 56 | | | |
| Oklahoma State | 59 | at | Pittsburgh | 21 | | | |
| Morgan State | 0 | at | Rutgers | 65 | | | |
| Stanford | 17 | at | San Diego State | 20 | | | |
| Alabama A&M | 0 | at | South Alabama | 45 | | | |
| Kentucky | 23 | at | South Carolina | 13 | | | |
| Texas | 24 | at | Southern California | 27 | 2OT | | |
| Central Michigan | 17 | at | Syracuse | 41 | | | |
| SMU | 36 | at | TCU | 56 | | | |
| UL Lafayette | 21 | at | Texas A&M | 45 | | | |
| Appalachian State | 20 | at | Texas State | 13 | | | |
| Arizona State | 45 | at | Texas Tech | 52 | | | |
| Southern | 17 | at | Texas-San Antonio | 51 | | | |
| Tulsa | 51 | at | Toledo | 54 | | | |
| North Carolina A&T | 35 | at | UNC-Charlotte | 31 | | | |
| San Jose State | 16 | at | Utah | 54 | | | |
| Kansas State | 7 | at | Vanderbilt | 14 | | | |
| Connecticut | 18 | at | Virginia | 38 | | | |
| Utah State | 10 | at | Wake Forest | 46 | | | |
| Fresno State | 16 | at | Washington | 48 | | | |
| Oregon State | 23 | at | Washington State | 52 | | | |
| Delaware State | 16 | at | West Virginia | 59 | | | |
| Louisiana Tech | 23 | at | Western Kentucky | 22 | | | |
| Idaho | 28 | at | Western Michigan | 37 | | | |
| Oregon | 49 | at | Wyoming | 13 | | | |
9/21/2017 | Temple | 7 | at | South Florida | 43 | | | |
9/22/2017 | Utah | 30 | at | Arizona | 24 | | | |
| Virginia | 42 | at | Boise State | 23 | | | |
9/23/2017 | San Diego State | 28 | at | Air Force | 24 | | | |
| Wake Forest | 20 | at | Appalachian State | 19 | | | |
| Oregon | 35 | at | Arizona State | 37 | | | |
| Texas A&M | 50 | vs | Arkansas | 43 | OT | Arlington TX | |
| Oklahoma | 49 | at | Baylor | 41 | | | |
| Florida Atlantic | 31 | at | Buffalo | 34 | | | |
| Southern California | 30 | at | California | 20 | | | |
| Miami-Ohio | 31 | at | Central Michigan | 14 | | | |
| Boston College | 7 | at | Clemson | 34 | | | |
| Western Illinois | 52 | at | Coastal Carolina | 10 | | | |
| Washington | 37 | at | Colorado | 10 | | | |
| Ohio | 27 | at | Eastern Michigan | 20 | 2OT | | |
| North Carolina State | 27 | at | Florida State | 21 | | | |
| Mississippi State | 3 | at | Georgia | 31 | | | |
| Pittsburgh | 17 | at | Georgia Tech | 35 | | | |
| Texas Tech | 27 | at | Houston | 24 | | | |
| Georgia Southern | 17 | at | Indiana | 52 | | | |
| Penn State | 21 | at | Iowa | 19 | | | |
| West Virginia | 56 | at | Kansas | 34 | | | |
| Florida | 28 | at | Kentucky | 27 | | | |
| UL Monroe | 56 | at | UL Lafayette | 50 | 2OT | | |
| Kent State | 3 | at | Louisville | 42 | | | |
| Syracuse | 26 | at | LSU | 35 | | | |
| UCF | 38 | at | Maryland | 10 | | | |
| Southern Illinois | 31 | at | Memphis | 44 | | | |
| Toledo | 30 | at | Miami-Florida | 52 | | | |
| Notre Dame | 38 | at | Michigan State | 18 | | | |
| Bowling Green | 13 | at | Middle Tenn State | 24 | | | |
| Auburn | 51 | at | Missouri | 14 | | | |
| Cincinnati | 32 | at | Navy | 42 | | | |
| Rutgers | 17 | at | Nebraska | 27 | | | |
| UTEP | 14 | at | New Mexico State | 41 | | | |
| Duke | 27 | at | North Carolina | 17 | | | |
| UAB | 43 | at | North Texas | 46 | | | |
| UNLV | 21 | at | Ohio State | 54 | | | |
| TCU | 44 | at | Oklahoma State | 31 | | | |
| Michigan | 28 | at | Purdue | 10 | | | |
| Florida Intl | 13 | at | Rice | 7 | | | |
| Utah State | 61 | at | San Jose State | 10 | | | |
| Arkansas State | 21 | at | SMU | 44 | | | |
| Idaho | 29 | at | South Alabama | 23 | 2OT | | |
| Louisiana Tech | 16 | at | South Carolina | 17 | | | |
| UCLA | 34 | at | Stanford | 58 | | | |
| Massachusetts | 13 | at | Tennessee | 17 | | | |
| Texas-San Antonio | 44 | at | Texas State | 14 | | | |
| Akron | 17 | at | Troy | 22 | | | |
| Army | 17 | at | Tulane | 21 | | | |
| New Mexico | 16 | at | Tulsa | 13 | | | |
| Georgia State | 28 | at | UNC-Charlotte | 0 | | | |
| Alabama | 59 | at | Vanderbilt | 0 | | | |
| Old Dominion | 0 | at | Virginia Tech | 38 | | | |
| Nevada | 7 | at | Washington State | 45 | | | |
| Ball State | 21 | at | Western Kentucky | 33 | | | |
| Wagner | 14 | at | Western Michigan | 49 | | | |
| Hawaii | 21 | at | Wyoming | 28 | OT | | |
9/24/2017 | East Carolina | 41 | at | Connecticut | 38 | | | |
9/28/2017 | Texas | 17 | at | Iowa State | 7 | | | |
9/29/2017 | Miami-Florida | 31 | at | Duke | 6 | | | |
| Nebraska | 28 | at | Illinois | 6 | | | |
| BYU | 24 | at | Utah State | 40 | | | |
| Southern California | 27 | at | Washington State | 30 | | | |
9/30/2017 | Mississippi | 3 | at | Alabama | 66 | | | |
| New Mexico State | 24 | at | Arkansas | 42 | | | |
| UTEP | 21 | at | Army | 35 | | | |
| Mississippi State | 10 | at | Auburn | 49 | | | |
| Central Michigan | 8 | at | Boston College | 28 | | | |
| Akron | 34 | at | Bowling Green | 23 | | | |
| Memphis | 13 | at | UCF | 40 | | | |
| Marshall | 38 | at | Cincinnati | 21 | | | |
| South Florida | 61 | at | East Carolina | 31 | | | |
| Vanderbilt | 24 | at | Florida | 38 | | | |
| Middle Tenn State | 20 | at | Florida Atlantic | 38 | | | |
| UNC-Charlotte | 29 | at | Florida Intl | 30 | | | |
| Nevada | 21 | at | Fresno State | 41 | | | |
| Memphis | | at | Georgia State | | | Cancelled | |
| North Carolina | 7 | at | Georgia Tech | 33 | | | |
| Colorado State | 51 | at | Hawaii | 21 | | | |
| Baylor | 20 | at | Kansas State | 33 | | | |
| Buffalo | 27 | at | Kent State | 13 | | | |
| Eastern Michigan | 20 | at | Kentucky | 24 | | | |
| South Alabama | 16 | at | Louisiana Tech | 34 | | | |
| Coastal Carolina | 43 | at | UL Monroe | 51 | | | |
| Murray State | 10 | at | Louisville | 55 | | | |
| Troy | 24 | at | LSU | 21 | | | |
| Ohio | 58 | at | Massachusetts | 50 | | | |
| Iowa | 10 | at | Michigan State | 17 | | | |
| Maryland | 31 | at | Minnesota | 24 | | | |
| Air Force | 38 | at | New Mexico | 56 | | | |
| Syracuse | 25 | at | North Carolina State | 33 | | | |
| Miami-Ohio | 17 | at | Notre Dame | 52 | | | |
| California | 24 | at | Oregon | 45 | | | |
| Washington | 42 | at | Oregon State | 7 | | | |
| Indiana | 14 | at | Penn State | 45 | | | |
| Rice | 10 | at | Pittsburgh | 42 | | | |
| Ohio State | 56 | at | Rutgers | 0 | | | |
| Northern Illinois | 28 | at | San Diego State | 34 | | | |
| Connecticut | 28 | at | SMU | 49 | | | |
| North Texas | 43 | at | Southern Miss | 28 | | | |
| Arizona State | 24 | at | Stanford | 34 | | | |
| Houston | 20 | at | Temple | 13 | | | |
| Georgia | 41 | at | Tennessee | 0 | | | |
| South Carolina | 17 | at | Texas A&M | 24 | | | |
| Oklahoma State | 41 | at | Texas Tech | 34 | | | |
| Navy | 31 | at | Tulsa | 21 | | | |
| Colorado | 23 | at | UCLA | 27 | | | |
| San Jose State | 13 | at | UNLV | 41 | | | |
| Clemson | 31 | at | Virginia Tech | 17 | | | |
| Florida State | 26 | at | Wake Forest | 19 | | | |
| Ball State | 3 | at | Western Michigan | 55 | | | |
| Northwestern | 24 | at | Wisconsin | 33 | | | |
| Texas State | 10 | at | Wyoming | 45 | | | |
10/4/2017 | Arkansas State | 43 | at | Georgia Southern | 25 | | | |
10/5/2017 | Louisville | 25 | at | North Carolina State | 39 | | | |
10/6/2017 | Boise State | 24 | at | BYU | 7 | | | |
| Memphis | 70 | at | Connecticut | 31 | | | |
10/7/2017 | Ball State | 3 | at | Akron | 31 | | | |
| Louisiana Tech | 22 | at | UAB | 23 | | | |
| New Mexico State | 31 | at | Appalachian State | 45 | | | |
| Mississippi | 23 | at | Auburn | 44 | | | |
| Virginia Tech | 23 | at | Boston College | 10 | | | |
| Western Michigan | 71 | at | Buffalo | 68 | 7OT | | |
| UCF | 51 | at | Cincinnati | 23 | | | |
| Wake Forest | 14 | at | Clemson | 28 | | | |
| Georgia State | 27 | at | Coastal Carolina | 21 | | | |
| Arizona | 45 | at | Colorado | 42 | | | |
| Temple | 34 | at | East Carolina | 10 | | | |
| LSU | 17 | at | Florida | 16 | | | |
| Miami-Florida | 24 | at | Florida State | 20 | | | |
| SMU | 22 | at | Houston | 35 | | | |
| UL Lafayette | 21 | at | Idaho | 16 | | | |
| Charleston Southern | 0 | at | Indiana | 27 | | | |
| Illinois | 16 | at | Iowa | 45 | | | |
| Texas Tech | 65 | at | Kansas | 19 | | | |
| Missouri | 34 | at | Kentucky | 40 | | | |
| Bowling Green | 37 | at | Miami-Ohio | 29 | | | |
| Michigan State | 14 | at | Michigan | 10 | | | |
| Florida Intl | 17 | at | Middle Tenn State | 37 | | | |
| Air Force | 45 | at | Navy | 48 | | | |
| Wisconsin | 38 | at | Nebraska | 17 | | | |
| Hawaii | 21 | at | Nevada | 35 | | | |
| Notre Dame | 33 | at | North Carolina | 10 | | | |
| Kent State | 3 | at | Northern Illinois | 24 | | | |
| Penn State | 31 | at | Northwestern | 7 | | | |
| Maryland | 14 | at | Ohio State | 62 | | | |
| Central Michigan | 26 | at | Ohio | 23 | | | |
| Iowa State | 38 | at | Oklahoma | 31 | | | |
| Florida Atlantic | 58 | at | Old Dominion | 28 | | | |
| Washington State | 33 | at | Oregon | 10 | | | |
| Minnesota | 17 | at | Purdue | 31 | | | |
| Army | 49 | at | Rice | 12 | | | |
| Fresno State | 27 | at | San Jose State | 10 | | | |
| Arkansas | 22 | at | South Carolina | 48 | | | |
| Oregon State | 10 | at | Southern California | 38 | | | |
| Pittsburgh | 24 | at | Syracuse | 27 | | | |
| West Virginia | 24 | at | TCU | 31 | | | |
| Kansas State | 34 | at | Texas | 40 | 2OT | | |
| Alabama | 27 | at | Texas A&M | 19 | | | |
| UL Monroe | 45 | at | Texas State | 27 | | | |
| Southern Miss | 31 | at | Texas-San Antonio | 29 | | | |
| Eastern Michigan | 15 | at | Toledo | 20 | | | |
| Tulsa | 28 | at | Tulane | 62 | | | |
| Marshall | 14 | at | UNC-Charlotte | 3 | | | |
| San Diego State | 41 | at | UNLV | 10 | | | |
| Stanford | 23 | at | Utah | 20 | | | |
| Colorado State | 27 | at | Utah State | 14 | | | |
| Western Kentucky | 15 | at | UTEP | 14 | | | |
| Georgia | 45 | at | Vanderbilt | 14 | | | |
| Duke | 21 | at | Virginia | 28 | | | |
| California | 7 | at | Washington | 38 | | | |
10/11/2017 | South Alabama | 19 | at | Troy | 8 | | | |
10/12/2017 | Texas State | 7 | at | UL Lafayette | 24 | | | |
10/13/2017 | Washington State | 3 | at | California | 37 | | | |
| Clemson | 24 | at | Syracuse | 27 | | | |
10/14/2017 | UNLV | 30 | at | Air Force | 34 | | | |
| Arkansas | 9 | at | Alabama | 41 | | | |
| Middle Tenn State | 23 | at | UAB | 25 | | | |
| UCLA | 30 | at | Arizona | 47 | | | |
| Washington | 7 | at | Arizona State | 13 | | | |
| Coastal Carolina | 17 | at | Arkansas State | 51 | | | |
| Eastern Michigan | 27 | at | Army | 28 | | | |
| Ohio | 48 | at | Bowling Green | 30 | | | |
| Northern Illinois | 14 | at | Buffalo | 13 | | | |
| East Carolina | 21 | at | UCF | 63 | | | |
| Toledo | 30 | at | Central Michigan | 10 | | | |
| Nevada | 42 | at | Colorado State | 44 | | | |
| Florida State | 17 | at | Duke | 10 | | | |
| Texas A&M | 19 | at | Florida | 17 | | | |
| Tulane | 10 | at | Florida Intl | 23 | | | |
| New Mexico | 0 | at | Fresno State | 38 | | | |
| Missouri | 28 | at | Georgia | 53 | | | |
| New Mexico State | 35 | at | Georgia Southern | 27 | | | |
| San Jose State | 26 | at | Hawaii | 37 | | | |
| Appalachian State | 23 | at | Idaho | 20 | | | |
| Rutgers | 35 | at | Illinois | 24 | | | |
| Michigan | 27 | at | Indiana | 20 | OT | | |
| Kansas | 0 | at | Iowa State | 45 | | | |
| TCU | 26 | at | Kansas State | 6 | | | |
| Miami-Ohio | 14 | at | Kent State | 17 | | | |
| Georgia State | 47 | at | UL Monroe | 37 | | | |
| Boston College | 45 | at | Louisville | 42 | | | |
| Auburn | 23 | at | LSU | 27 | | | |
| Old Dominion | 3 | at | Marshall | 35 | | | |
| Northwestern | 37 | at | Maryland | 21 | | | |
| Navy | 27 | at | Memphis | 30 | | | |
| Georgia Tech | 24 | at | Miami-Florida | 25 | | | |
| Michigan State | 30 | at | Minnesota | 27 | | | |
| Vanderbilt | 35 | at | Mississippi | 57 | | | |
| BYU | 10 | at | Mississippi State | 35 | | | |
| Ohio State | 56 | at | Nebraska | 14 | | | |
| Virginia | 20 | at | North Carolina | 14 | | | |
| Texas-San Antonio | 26 | at | North Texas | 29 | | | |
| Baylor | 16 | at | Oklahoma State | 59 | | | |
| Colorado | 36 | at | Oregon State | 33 | | | |
| North Carolina State | 35 | at | Pittsburgh | 17 | | | |
| Boise State | 31 | at | San Diego State | 14 | | | |
| Massachusetts | | at | South Florida | | | Cancelled | |
| Cincinnati | 3 | at | South Florida | 33 | | | |
| Utah | 27 | at | Southern California | 28 | | | |
| UTEP | 0 | at | Southern Miss | 24 | | | |
| Oregon | 7 | at | Stanford | 49 | | | |
| Connecticut | 28 | at | Temple | 24 | | | |
| South Carolina | 15 | at | Tennessee | 9 | | | |
| Oklahoma | 29 | vs | Texas | 24 | | Dallas TX | |
| Houston | 17 | at | Tulsa | 45 | | | |
| Wyoming | 28 | at | Utah State | 23 | | | |
| Texas Tech | 35 | at | West Virginia | 46 | | | |
| UNC-Charlotte | 14 | at | Western Kentucky | 45 | | | |
| Akron | | at | Western Michigan | | | Postponed | |
| Purdue | 9 | at | Wisconsin | 17 | | | |
10/15/2017 | Akron | 14 | at | Western Michigan | 13 | | | |
10/19/2017 | UL Lafayette | 3 | at | Arkansas State | 47 | | | |
| Memphis | 42 | at | Houston | 38 | | | |
10/20/2017 | Marshall | 38 | at | Middle Tenn State | 10 | | | |
| Air Force | 45 | at | Nevada | 42 | | | |
| Colorado State | 27 | at | New Mexico | 24 | | | |
| Western Kentucky | 35 | at | Old Dominion | 31 | | | |
10/21/2017 | Tennessee | 7 | at | Alabama | 45 | | | |
| Coastal Carolina | 29 | at | Appalachian State | 37 | | | |
| Auburn | 52 | at | Arkansas | 20 | | | |
| Temple | 28 | at | Army | 31 | OT | | |
| Central Michigan | 56 | at | Ball State | 9 | | | |
| West Virginia | 38 | at | Baylor | 36 | | | |
| Wyoming | 14 | at | Boise State | 24 | | | |
| Northern Illinois | 48 | at | Bowling Green | 17 | | | |
| Arizona | 45 | at | California | 44 | 2OT | | |
| SMU | 31 | at | Cincinnati | 28 | OT | | |
| Tulsa | 14 | at | Connecticut | 20 | | | |
| Pittsburgh | 24 | at | Duke | 17 | | | |
| BYU | 17 | at | East Carolina | 33 | | | |
| Western Michigan | 20 | at | Eastern Michigan | 17 | OT | | |
| North Texas | 31 | at | Florida Atlantic | 69 | | | |
| Louisville | 31 | at | Florida State | 28 | | | |
| Troy | 34 | at | Georgia State | 10 | | | |
| Wake Forest | 24 | at | Georgia Tech | 38 | | | |
| Oklahoma | 42 | at | Kansas State | 35 | | | |
| Southern Miss | 34 | at | Louisiana Tech | 27 | 2OT | | |
| Georgia Southern | 20 | at | Massachusetts | 55 | | | |
| Syracuse | 19 | at | Miami-Florida | 27 | | | |
| Buffalo | 14 | at | Miami-Ohio | 24 | | | |
| Indiana | 9 | at | Michigan State | 17 | | | |
| Illinois | 17 | at | Minnesota | 24 | | | |
| LSU | 40 | at | Mississippi | 24 | | | |
| Kentucky | 7 | at | Mississippi State | 45 | | | |
| Idaho | 21 | at | Missouri | 68 | | | |
| UCF | 31 | at | Navy | 21 | | | |
| Iowa | 10 | at | Northwestern | 17 | | | |
| Southern California | 14 | at | Notre Dame | 49 | | | |
| Kent State | 3 | at | Ohio | 48 | | | |
| Michigan | 13 | at | Penn State | 42 | | | |
| Purdue | 12 | at | Rutgers | 14 | | | |
| Fresno State | 27 | at | San Diego State | 3 | | | |
| UL Monroe | 23 | at | South Alabama | 33 | | | |
| Kansas | 0 | at | TCU | 43 | | | |
| Oklahoma State | 13 | at | Texas | 10 | OT | | |
| Iowa State | 31 | at | Texas Tech | 13 | | | |
| Rice | 7 | at | Texas-San Antonio | 20 | | | |
| Akron | 21 | at | Toledo | 48 | | | |
| South Florida | 34 | at | Tulane | 28 | | | |
| Oregon | 14 | at | UCLA | 31 | | | |
| UAB | 24 | at | UNC-Charlotte | 25 | OT | | |
| Utah State | 52 | at | UNLV | 28 | | | |
| Arizona State | 30 | at | Utah | 10 | | | |
| Boston College | 41 | at | Virginia | 10 | | | |
| North Carolina | 7 | at | Virginia Tech | 59 | | | |
| Colorado | 0 | at | Washington State | 28 | | | |
| Maryland | 13 | at | Wisconsin | 38 | | | |
10/26/2017 | Toledo | 58 | at | Ball State | 17 | | | |
| South Alabama | 13 | at | Georgia State | 21 | | | |
| Eastern Michigan | 27 | at | Northern Illinois | 30 | OT | | |
| Stanford | 15 | at | Oregon State | 14 | | | |
10/27/2017 | Florida State | 3 | at | Boston College | 35 | | | |
| Tulane | 26 | at | Memphis | 56 | | | |
| Tulsa | 34 | at | SMU | 38 | | | |
10/28/2017 | Buffalo | 20 | at | Akron | 21 | | | |
| Washington State | 37 | at | Arizona | 58 | | | |
| Southern California | 48 | at | Arizona State | 17 | | | |
| Texas | 38 | at | Baylor | 7 | | | |
| San Jose State | 20 | at | BYU | 41 | | | |
| Austin Peay | 33 | at | UCF | 73 | | | |
| Georgia Tech | 10 | at | Clemson | 24 | | | |
| Texas State | 27 | at | Coastal Carolina | 7 | | | |
| California | 28 | at | Colorado | 44 | | | |
| Air Force | 45 | at | Colorado State | 28 | | | |
| Missouri | 52 | at | Connecticut | 12 | | | |
| Georgia | 42 | vs | Florida | 7 | | Jacksonville FL | |
| UNLV | 26 | at | Fresno State | 16 | | | |
| San Diego State | 28 | at | Hawaii | 7 | | | |
| UL Monroe | 23 | at | Idaho | 31 | | | |
| Wisconsin | 24 | at | Illinois | 10 | | | |
| Minnesota | 10 | at | Iowa | 17 | | | |
| TCU | 7 | at | Iowa State | 14 | | | |
| Kansas State | 30 | at | Kansas | 20 | | | |
| Tennessee | 26 | at | Kentucky | 29 | | | |
| Florida Intl | 41 | at | Marshall | 30 | | | |
| Indiana | 39 | at | Maryland | 42 | | | |
| Appalachian State | 27 | at | Massachusetts | 30 | | | |
| Rutgers | 14 | at | Michigan | 35 | | | |
| Arkansas | 38 | at | Mississippi | 37 | | | |
| Arkansas State | 37 | at | New Mexico State | 21 | | | |
| Miami-Florida | 24 | at | North Carolina | 19 | | | |
| Old Dominion | 38 | at | North Texas | 45 | | | |
| Michigan State | 31 | at | Northwestern | 39 | 3OT | | |
| North Carolina State | 14 | at | Notre Dame | 35 | | | |
| Penn State | 38 | at | Ohio State | 39 | | | |
| Texas Tech | 27 | at | Oklahoma | 49 | | | |
| Utah | 20 | at | Oregon | 41 | | | |
| Virginia | 14 | at | Pittsburgh | 31 | | | |
| Nebraska | 25 | at | Purdue | 24 | | | |
| Louisiana Tech | 42 | at | Rice | 28 | | | |
| Vanderbilt | 27 | at | South Carolina | 34 | | | |
| Houston | 28 | at | South Florida | 24 | | | |
| UAB | 30 | at | Southern Miss | 12 | | | |
| Mississippi State | 35 | at | Texas A&M | 14 | | | |
| Georgia Southern | 16 | at | Troy | 38 | | | |
| Boise State | 41 | at | Utah State | 14 | | | |
| Texas-San Antonio | 31 | at | UTEP | 14 | | | |
| Duke | 3 | at | Virginia Tech | 24 | | | |
| Louisville | 32 | at | Wake Forest | 42 | | | |
| UCLA | 23 | at | Washington | 44 | | | |
| Oklahoma State | 50 | at | West Virginia | 39 | | | |
| Florida Atlantic | 42 | at | Western Kentucky | 28 | | | |
| New Mexico | 3 | at | Wyoming | 42 | | | |
10/31/2017 | Bowling Green | 44 | at | Kent State | 16 | | | |
| Miami-Ohio | 28 | at | Ohio | 45 | | | |
11/1/2017 | Central Michigan | 35 | at | Western Michigan | 28 | | | |
11/2/2017 | Ball State | 14 | at | Eastern Michigan | 56 | | | |
| Navy | 26 | at | Temple | 34 | | | |
| Northern Illinois | 17 | at | Toledo | 27 | | | |
| Idaho | 21 | at | Troy | 24 | | | |
11/3/2017 | Marshall | 25 | at | Florida Atlantic | 30 | | | |
| Memphis | 41 | at | Tulsa | 14 | | | |
| UCLA | 17 | at | Utah | 48 | | | |
11/4/2017 | Army | 21 | at | Air Force | 0 | | | |
| LSU | 10 | at | Alabama | 24 | | | |
| Rice | 21 | at | UAB | 52 | | | |
| Colorado | 30 | at | Arizona State | 41 | | | |
| Coastal Carolina | 38 | at | Arkansas | 39 | | | |
| Nevada | 14 | at | Boise State | 41 | | | |
| Oregon State | 23 | at | California | 37 | | | |
| South Florida | 37 | at | Connecticut | 20 | | | |
| Texas-San Antonio | 7 | at | Florida Intl | 14 | | | |
| Syracuse | 24 | at | Florida State | 27 | | | |
| BYU | 13 | at | Fresno State | 20 | | | |
| South Carolina | 10 | at | Georgia | 24 | | | |
| Georgia State | 21 | at | Georgia Southern | 17 | | | |
| East Carolina | 27 | at | Houston | 52 | | | |
| Wisconsin | 45 | at | Indiana | 17 | | | |
| Ohio State | 24 | at | Iowa | 55 | | | |
| Baylor | 38 | at | Kansas | 9 | | | |
| Mississippi | 37 | at | Kentucky | 34 | | | |
| North Texas | 24 | at | Louisiana Tech | 23 | | | |
| Appalachian State | 45 | at | UL Monroe | 52 | | | |
| Virginia Tech | 10 | at | Miami-Florida | 28 | | | |
| Minnesota | 10 | at | Michigan | 33 | | | |
| Penn State | 24 | at | Michigan State | 27 | | | |
| UTEP | 3 | at | Middle Tenn State | 30 | | | |
| Massachusetts | 23 | at | Mississippi State | 34 | | | |
| Florida | 16 | at | Missouri | 45 | | | |
| Northwestern | 31 | at | Nebraska | 24 | OT | | |
| Utah State | 24 | at | New Mexico | 10 | | | |
| Clemson | 38 | at | North Carolina State | 31 | | | |
| Wake Forest | 37 | at | Notre Dame | 48 | | | |
| Oklahoma | 62 | at | Oklahoma State | 52 | | | |
| UNC-Charlotte | 0 | at | Old Dominion | 6 | | | |
| Illinois | 10 | at | Purdue | 29 | | | |
| Maryland | 24 | at | Rutgers | 31 | | | |
| San Diego State | 52 | at | San Jose State | 7 | | | |
| UCF | 31 | at | SMU | 24 | | | |
| UL Lafayette | 19 | at | South Alabama | 14 | | | |
| Arizona | 35 | at | Southern California | 49 | | | |
| Texas | 7 | at | TCU | 24 | | | |
| Southern Miss | 10 | at | Tennessee | 24 | | | |
| Auburn | 42 | at | Texas A&M | 27 | | | |
| New Mexico State | 45 | at | Texas State | 35 | | | |
| Kansas State | 42 | at | Texas Tech | 35 | OT | | |
| Cincinnati | 17 | at | Tulane | 16 | | | |
| Hawaii | 23 | at | UNLV | 31 | | | |
| Western Kentucky | 17 | at | Vanderbilt | 31 | | | |
| Georgia Tech | 36 | at | Virginia | 40 | | | |
| Oregon | 3 | at | Washington | 38 | | | |
| Stanford | 21 | at | Washington State | 24 | | | |
| Iowa State | 16 | at | West Virginia | 20 | | | |
| Colorado State | 13 | at | Wyoming | 16 | | | |
11/7/2017 | Bowling Green | 28 | at | Buffalo | 38 | | | |
| Akron | 14 | at | Miami-Ohio | 24 | | | |
11/8/2017 | Eastern Michigan | 30 | at | Central Michigan | 42 | | | |
| Toledo | 10 | at | Ohio | 38 | | | |
| Kent State | 20 | at | Western Michigan | 48 | | | |
11/9/2017 | Georgia Southern | 6 | at | Appalachian State | 27 | | | |
| Ball State | 17 | at | Northern Illinois | 63 | | | |
| North Carolina | 34 | at | Pittsburgh | 31 | | | |
11/10/2017 | Temple | 35 | at | Cincinnati | 24 | | | |
| Washington | 22 | at | Stanford | 30 | | | |
| BYU | 31 | at | UNLV | 21 | | | |
11/11/2017 | Wyoming | 28 | at | Air Force | 14 | | | |
| Oregon State | 28 | at | Arizona | 49 | | | |
| Duke | 16 | at | Army | 21 | | | |
| Georgia | 17 | at | Auburn | 40 | | | |
| Texas Tech | 38 | vs | Baylor | 24 | | Arlington TX | |
| North Carolina State | 17 | at | Boston College | 14 | | | |
| Connecticut | 24 | at | UCF | 49 | | | |
| Florida State | 14 | at | Clemson | 31 | | | |
| Troy | 42 | at | Coastal Carolina | 17 | | | |
| Southern California | 38 | at | Colorado | 24 | | | |
| Boise State | 59 | at | Colorado State | 52 | OT | | |
| Tulane | 31 | at | East Carolina | 24 | OT | | |
| Old Dominion | 37 | at | Florida Intl | 30 | | | |
| Virginia Tech | 22 | at | Georgia Tech | 28 | | | |
| Fresno State | 31 | at | Hawaii | 21 | | | |
| Indiana | 24 | at | Illinois | 14 | | | |
| Oklahoma State | 49 | at | Iowa State | 42 | | | |
| West Virginia | 28 | at | Kansas State | 23 | | | |
| Florida Atlantic | 48 | at | Louisiana Tech | 23 | | | |
| Virginia | 21 | at | Louisville | 38 | | | |
| Arkansas | 10 | at | LSU | 33 | | | |
| Western Kentucky | 23 | at | Marshall | 30 | | | |
| Michigan | 35 | at | Maryland | 10 | | | |
| Maine | 31 | vs | Massachusetts | 44 | | Boston MA | |
| Notre Dame | 8 | at | Miami-Florida | 41 | | | |
| Nebraska | 21 | at | Minnesota | 54 | | | |
| UL Lafayette | 22 | at | Mississippi | 50 | | | |
| Alabama | 31 | at | Mississippi State | 24 | | | |
| Tennessee | 17 | at | Missouri | 50 | | | |
| SMU | 40 | at | Navy | 43 | | | |
| San Jose State | 14 | at | Nevada | 59 | | | |
| UTEP | 10 | at | North Texas | 45 | | | |
| Purdue | 13 | at | Northwestern | 23 | | | |
| Michigan State | 3 | at | Ohio State | 48 | | | |
| TCU | 20 | at | Oklahoma | 38 | | | |
| Rutgers | 6 | at | Penn State | 35 | | | |
| Southern Miss | 43 | at | Rice | 34 | | | |
| Arkansas State | 19 | at | South Alabama | 24 | | | |
| Florida | 20 | at | South Carolina | 28 | | | |
| Wake Forest | 64 | at | Syracuse | 43 | | | |
| Kansas | 27 | at | Texas | 42 | | | |
| New Mexico | 14 | at | Texas A&M | 55 | | | |
| Georgia State | 33 | at | Texas State | 30 | | | |
| UAB | 24 | at | Texas-San Antonio | 19 | | | |
| Arizona State | 37 | at | UCLA | 44 | | | |
| Middle Tenn State | 35 | at | UNC-Charlotte | 21 | | | |
| Washington State | 33 | at | Utah | 25 | | | |
| Kentucky | 44 | at | Vanderbilt | 21 | | | |
| Iowa | 14 | at | Wisconsin | 38 | | | |
11/14/2017 | Ohio | 34 | at | Akron | 37 | | | |
| Central Michigan | 42 | at | Kent State | 23 | | | |
11/15/2017 | Toledo | 66 | at | Bowling Green | 37 | | | |
| Eastern Michigan | 27 | at | Miami-Ohio | 24 | | | |
| Western Michigan | 31 | at | Northern Illinois | 35 | | | |
11/16/2017 | Buffalo | 40 | at | Ball State | 24 | | | |
| Tulsa | 20 | at | South Florida | 27 | | | |
11/17/2017 | UNLV | 38 | at | New Mexico | 35 | | | |
| Middle Tenn State | 38 | at | Western Kentucky | 41 | | | |
11/18/2017 | Mercer | 0 | at | Alabama | 56 | | | |
| Mississippi State | 28 | at | Arkansas | 21 | | | |
| Texas State | 12 | at | Arkansas State | 30 | | | |
| UL Monroe | 14 | at | Auburn | 42 | | | |
| Iowa State | 23 | at | Baylor | 13 | | | |
| Air Force | 19 | at | Boise State | 44 | | | |
| Massachusetts | 16 | at | BYU | 10 | | | |
| The Citadel | 3 | at | Clemson | 61 | | | |
| San Jose State | 14 | at | Colorado State | 42 | | | |
| Boston College | 39 | vs | Connecticut | 16 | | Boston MA | |
| Georgia Tech | 20 | at | Duke | 43 | | | |
| Cincinnati | 20 | at | East Carolina | 48 | | | |
| UAB | 7 | at | Florida | 36 | | | |
| Florida Intl | 24 | at | Florida Atlantic | 52 | | | |
| Delaware State | 6 | at | Florida State | 77 | | | |
| Kentucky | 13 | at | Georgia | 42 | | | |
| South Alabama | 0 | at | Georgia Southern | 52 | | | |
| Coastal Carolina | 13 | at | Idaho | 7 | | | |
| Rutgers | 0 | at | Indiana | 41 | | | |
| Purdue | 24 | at | Iowa | 15 | | | |
| Oklahoma | 41 | at | Kansas | 3 | | | |
| New Mexico State | 34 | at | UL Lafayette | 47 | | | |
| Syracuse | 10 | at | Louisville | 56 | | | |
| SMU | 45 | at | Memphis | 66 | | | |
| Virginia | 28 | at | Miami-Florida | 44 | | | |
| Maryland | 7 | at | Michigan State | 17 | | | |
| Texas A&M | 31 | at | Mississippi | 24 | | | |
| Western Carolina | 10 | at | North Carolina | 65 | | | |
| Army | 49 | at | North Texas | 52 | | | |
| Minnesota | 0 | at | Northwestern | 39 | | | |
| Navy | 17 | at | Notre Dame | 24 | | | |
| Illinois | 14 | at | Ohio State | 52 | | | |
| Kansas State | 45 | at | Oklahoma State | 40 | | | |
| Rice | 21 | at | Old Dominion | 24 | | | |
| Arizona | 28 | at | Oregon | 48 | | | |
| Arizona State | 40 | at | Oregon State | 24 | | | |
| Nebraska | 44 | at | Penn State | 56 | | | |
| Nevada | 23 | at | San Diego State | 42 | | | |
| Wofford | 10 | at | South Carolina | 31 | | | |
| UCLA | 23 | at | Southern California | 28 | | | |
| UNC-Charlotte | 21 | at | Southern Miss | 66 | | | |
| California | 14 | at | Stanford | 17 | | | |
| UCF | 45 | at | Temple | 19 | | | |
| LSU | 30 | at | Tennessee | 10 | | | |
| TCU | 27 | at | Texas Tech | 3 | | | |
| Marshall | 7 | at | Texas-San Antonio | 9 | | | |
| Houston | 17 | at | Tulane | 20 | | | |
| Hawaii | 0 | at | Utah State | 38 | | | |
| Louisiana Tech | 42 | at | UTEP | 21 | | | |
| Missouri | 45 | at | Vanderbilt | 17 | | | |
| Pittsburgh | 14 | at | Virginia Tech | 20 | | | |
| North Carolina State | 24 | at | Wake Forest | 30 | | | |
| Utah | 30 | at | Washington | 33 | | | |
| Texas | 28 | at | West Virginia | 14 | | | |
| Michigan | 10 | at | Wisconsin | 24 | | | |
| Fresno State | 13 | at | Wyoming | 7 | | | |
11/21/2017 | Kent State | 14 | at | Akron | 24 | | | |
| Miami-Ohio | 28 | at | Ball State | 7 | | | |
| Bowling Green | 31 | at | Eastern Michigan | 34 | | | |
11/23/2017 | Mississippi | 31 | at | Mississippi State | 28 | | | |
11/24/2017 | Missouri | 48 | at | Arkansas | 45 | | | |
| Ohio | 24 | at | Buffalo | 31 | | | |
| South Florida | 42 | at | UCF | 49 | | | |
| Northern Illinois | 24 | at | Central Michigan | 31 | | | |
| Western Kentucky | 17 | at | Florida Intl | 41 | | | |
| Navy | 14 | at | Houston | 24 | | | |
| Iowa | 56 | at | Nebraska | 14 | | | |
| Miami-Florida | 14 | at | Pittsburgh | 24 | | | |
| New Mexico | 10 | at | San Diego State | 35 | | | |
| Baylor | 22 | at | TCU | 45 | | | |
| Texas Tech | 27 | at | Texas | 23 | | | |
| Western Michigan | 10 | at | Toledo | 37 | | | |
| Texas State | 9 | at | Troy | 62 | | | |
| California | 27 | at | UCLA | 30 | | | |
| Virginia Tech | 10 | at | Virginia | 0 | | | |
11/25/2017 | Utah State | 35 | at | Air Force | 38 | | | |
| UTEP | 7 | at | UAB | 28 | | | |
| Arizona | 30 | at | Arizona State | 42 | | | |
| Alabama | 14 | at | Auburn | 26 | | | |
| Connecticut | 21 | at | Cincinnati | 22 | | | |
| Florida State | 38 | at | Florida | 22 | | | |
| Boise State | 17 | at | Fresno State | 28 | | | |
| Appalachian State | 31 | at | Georgia State | 10 | | | |
| Georgia | 38 | at | Georgia Tech | 7 | | | |
| BYU | 30 | at | Hawaii | 20 | | | |
| Northwestern | 42 | at | Illinois | 7 | | | |
| Iowa State | 19 | at | Kansas State | 20 | | | |
| Louisville | 44 | at | Kentucky | 17 | | | |
| Texas-San Antonio | 6 | at | Louisiana Tech | 20 | | | |
| Georgia Southern | 34 | at | UL Lafayette | 24 | | | |
| Arkansas State | 67 | at | UL Monroe | 50 | | | |
| Texas A&M | 21 | at | LSU | 45 | | | |
| Southern Miss | 28 | at | Marshall | 27 | | | |
| Penn State | 66 | at | Maryland | 3 | | | |
| East Carolina | 13 | at | Memphis | 70 | | | |
| Ohio State | 31 | at | Michigan | 20 | | | |
| Old Dominion | 10 | at | Middle Tenn State | 41 | | | |
| Wisconsin | 31 | at | Minnesota | 0 | | | |
| UNLV | 16 | at | Nevada | 23 | | | |
| Idaho | 10 | at | New Mexico State | 17 | | | |
| North Carolina | 21 | at | North Carolina State | 33 | | | |
| West Virginia | 31 | at | Oklahoma | 59 | | | |
| Kansas | 17 | at | Oklahoma State | 58 | | | |
| Oregon State | 10 | at | Oregon | 69 | | | |
| Indiana | 24 | at | Purdue | 31 | | | |
| North Texas | 30 | at | Rice | 14 | | | |
| Michigan State | 40 | at | Rutgers | 7 | | | |
| Wyoming | 17 | at | San Jose State | 20 | | | |
| Tulane | 38 | at | SMU | 41 | | | |
| Clemson | 34 | at | South Carolina | 10 | | | |
| Notre Dame | 20 | at | Stanford | 38 | | | |
| Boston College | 42 | at | Syracuse | 14 | | | |
| Vanderbilt | 42 | at | Tennessee | 24 | | | |
| Temple | 43 | at | Tulsa | 22 | | | |
| Florida Atlantic | 31 | at | UNC-Charlotte | 12 | | | |
| Colorado | 13 | at | Utah | 34 | | | |
| Duke | 31 | at | Wake Forest | 23 | | | |
| Washington State | 14 | at | Washington | 41 | | | |
12/1/2017 | Stanford | 28 | vs | Southern California | 31 | | Pac 12 Championship (Santa Clara CA) | |
12/2/2017 | UL Lafayette | 14 | at | Appalachian State | 63 | | | |
| Troy | 32 | at | Arkansas State | 25 | | | |
| Georgia | 28 | vs | Auburn | 7 | | SEC Championship (Atlanta GA) | |
| Fresno State | 14 | at | Boise State | 17 | | Mountain West Championship | |
| Memphis | 55 | at | UCF | 62 | 2OT | AAC Championship | |
| Miami-Florida | 3 | vs | Clemson | 38 | | ACC Championhship (Charlotte NC) | |
| Georgia Southern | 17 | at | Coastal Carolina | 28 | | | |
| North Texas | 17 | at | Florida Atlantic | 41 | | CUSA Championship | |
| Massachusetts | 45 | at | Florida Intl | 63 | | | |
| UL Monroe | 10 | at | Florida State | 42 | | | |
| Idaho | 24 | at | Georgia State | 10 | | | |
| South Alabama | 17 | at | New Mexico State | 22 | | | |
| TCU | 17 | vs | Oklahoma | 41 | | Big12 Championship (Arlington TX) | |
| Akron | 28 | vs | Toledo | 45 | | MAC Championship (Detroit MI) | |
| Ohio State | 27 | vs | Wisconsin | 21 | | Big10 Championship (Indianapolis IN) | |
12/9/2017 | Army | 14 | vs | Navy | 13 | | Philadelphia PA | |
12/16/2017 | Middle Tenn State | 35 | vs | Arkansas State | 30 | | Camelia Bowl (Montgomery AL) | |
| Marshall | 31 | vs | Colorado State | 28 | | New Mexico Bowl (Albuquerque NM) | |
| Western Kentucky | 17 | vs | Georgia State | 27 | | Cure Bowl (Orlando FL) | |
| Troy | 50 | vs | North Texas | 30 | | New Orleans Bowl (New Orleans LA) | |
| Boise State | 38 | vs | Oregon | 28 | | Las Vegas Bowl (Las Vegas NV) | |
12/19/2017 | Akron | 3 | vs | Florida Atlantic | 50 | | Boca Raton Bowl (Boca Raton FL) | |
12/20/2017 | Louisiana Tech | 51 | vs | SMU | 10 | | Frisco Bowl (Frisco TX) | |
12/21/2017 | Temple | 28 | vs | Florida Intl | 3 | | Gasparilla Bowl (Saint Petersburg FL) | |
12/22/2017 | UAB | 6 | vs | Ohio | 41 | | Bahamas Bowl (Nassau NP) | |
| Central Michigan | 14 | vs | Wyoming | 37 | | Famous Idaho Potato Bowl (Boise ID) | |
12/23/2017 | San Diego State | 35 | vs | Army | 42 | | Armed Forces Bowl (Fort Worth TX) | |
| Texas Tech | 34 | vs | South Florida | 38 | | Birmingham Bowl (Birmingham AL) | |
| Appalachian State | 34 | vs | Toledo | 0 | | Dollar General Bowl (Mobile AL) | |
12/24/2017 | Fresno State | 33 | vs | Houston | 27 | | Hawaii Bowl (Honolulu HA) | |
12/26/2017 | Duke | 36 | vs | Northern Illinois | 14 | | Quick Lane Bowl (Detroit MI) | |
| Kansas State | 35 | vs | UCLA | 17 | | Cactus Bowl (Phoenix AZ) | |
| Utah | 30 | vs | West Virginia | 14 | | Heart of Dallas Bowl (Dallas TX) | |
12/27/2017 | Iowa | 27 | vs | Boston College | 20 | | Pinstripe Bowl (New York NY) | |
| Southern Miss | 13 | vs | Florida State | 42 | | Independence Bowl (Shreveport LA) | |
| Texas | 33 | vs | Missouri | 16 | | Texas Bowl (Houston TX) | |
| Arizona | 35 | vs | Purdue | 38 | | Foster Farms Bowl (Santa Clasra CA) | |
12/28/2017 | Washington State | 17 | vs | Michigan State | 42 | | Holiday Bowl (San Diego) | |
| Virginia | 7 | vs | Navy | 49 | | Military Bowl (Annapolis TX) | |
| Virginia Tech | 21 | vs | Oklahoma State | 30 | | Camping World Bowl (Orlando FL) | |
| Stanford | 37 | vs | TCU | 39 | | Alamo Bowl (San Antonio TX) | |
12/29/2017 | North Carolina State | 52 | vs | Arizona State | 31 | | Sun Bowl (El Paso TX) | |
| Kentucky | 23 | vs | Northwestern | 24 | | Music City Bowl (Nashville TN) | |
| Southern California | 7 | vs | Ohio State | 24 | | Cotton Bowl (Arlington TX) | |
| Wake Forest | 55 | vs | Texas A&M | 52 | | Belk Bowl (Charlotte NC) | |
| New Mexico State | 26 | vs | Utah State | 20 | OT | Arizona Bowl (Tuscon AZ) | |
12/30/2017 | Iowa State | 21 | vs | Memphis | 20 | | Liberty Bowl (Memphis TN) | |
| Wisconsin | 34 | vs | Miami-Florida | 24 | | Orange Bowl (Miami FL) | |
| Louisville | 27 | vs | Mississippi State | 31 | | Taxslayer Bowl (Jacksonville FL) | |
| Washington | 28 | vs | Penn State | 35 | | Fiesta Bowl (Glendale AZ) | |
1/1/2018 | UCF | 34 | vs | Auburn | 27 | | Peach Bowl (Atlanta GA) | |
| Alabama | 24 | vs | Clemson | 6 | | Sugar Bowl (New Orleans LA) | |
| Notre Dame | 21 | vs | LSU | 17 | | Citrus Bowl (Orlanda FL) | |
| Georgia | 54 | vs | Oklahoma | 48 | 2OT | Rose Bowl (Pasadena CA) | |
| Michigan | 19 | vs | South Carolina | 26 | | Outback Bowl (Tampa FL) | |
1/8/2018 | Alabama | 26 | vs | Georgia | 23 | OT | 1A Championship (Atlanta GA) | |