| 9/2/2017 | Stephen F. Austin (4-7) | 14 | at | SMU | 58 | SLC (1AA) | ||
| 9/9/2017 | North Texas (9-5) | 32 | at | SMU | 54 | CUSA | ||
| 9/16/2017 | SMU | 36 | at | TCU (11-3) | 56 | at B12 | ||
| 9/23/2017 | Arkansas State (7-5) | 21 | at | SMU | 44 | SBC | ||
| 9/30/2017 | Connecticut (3-9,2-6) | 28 | at | SMU | 49 | |||
| 10/7/2017 | SMU | 22 | at | Houston (7-5,5-3) | 35 | |||
| 10/21/2017 | SMU | 31 | at | Cincinnati (4-8,2-6) | 28 | OT | ||
| 10/27/2017 | Tulsa (2-10,1-7) | 34 | at | SMU | 38 | |||
| 11/4/2017 | UCF (13-0,9-0) | 31 | at | SMU | 24 | |||
| 11/11/2017 | SMU | 40 | at | Navy (7-6,4-4) | 43 | |||
| 11/18/2017 | SMU | 45 | at | Memphis (10-3,7-2) | 66 | |||
| 11/25/2017 | Tulane (5-7,3-5) | 38 | at | SMU | 41 | |||
| 12/20/2017 | Louisiana Tech (7-6) | 51 | vs | SMU | 10 | Frisco Bowl (Frisco TX) | CUSA |
| vs SMU | vs Other Opponents | SMU compared to OOs | |
| Record: | 6-7 | 83-67 | |
| Points Scored: | 36.69 | 31.51 | -5.18 |
| Points Allowed: | 37.85 | 28.29 | 9.56 |
| Margin: | -1.16 | 3.22 | 4.38 |
| Total Points: | 74.54 | 59.80 | 14.74 |