| 9/2/2017 | Jackson State (3-8) | 0 | at | TCU | 63 | | | SWAC (1AA) |
| 9/9/2017 | TCU | 28 | at | Arkansas (4-8) | 7 | | | at SEC |
| 9/16/2017 | SMU (7-6) | 36 | at | TCU | 56 | | | AAC |
| 9/23/2017 | TCU | 44 | at | Oklahoma State (10-3,6-3) | 31 | | | |
| 10/7/2017 | West Virginia (7-6,5-4) | 24 | at | TCU | 31 | | | |
| 10/14/2017 | TCU | 26 | at | Kansas State (8-5,5-4) | 6 | | | |
| 10/21/2017 | Kansas (1-11,0-9) | 0 | at | TCU | 43 | | | |
| 10/28/2017 | TCU | 7 | at | Iowa State (8-5,5-4) | 14 | | | |
| 11/4/2017 | Texas (7-6,5-4) | 7 | at | TCU | 24 | | | |
| 11/11/2017 | TCU | 20 | at | Oklahoma (12-2,9-1) | 38 | | | |
| 11/18/2017 | TCU | 27 | at | Texas Tech (6-7,3-6) | 3 | | | |
| 11/24/2017 | Baylor (1-11,1-8) | 22 | at | TCU | 45 | | | |
| 12/2/2017 | TCU | 17 | vs | Oklahoma (12-2,9-1) | 41 | | Big12 Championship (Arlington TX) | |
| 12/28/2017 | Stanford (9-5) | 37 | vs | TCU | 39 | | Alamo Bowl (San Antonio TX) | P12 |