| 9/2/2017 | Northwestern State (4-7) | 24 | at | Louisiana Tech | 52 | SLC (1AA) | ||
| 9/9/2017 | Mississippi State (9-4) | 57 | at | Louisiana Tech | 21 | SEC | ||
| 9/16/2017 | Louisiana Tech | 23 | at | Western Kentucky (6-7,4-4) | 22 | |||
| 9/23/2017 | Louisiana Tech | 16 | at | South Carolina (9-4) | 17 | at SEC | ||
| 9/30/2017 | South Alabama (4-8) | 16 | at | Louisiana Tech | 34 | SBC | ||
| 10/7/2017 | Louisiana Tech | 22 | at | UAB (8-5,6-2) | 23 | |||
| 10/21/2017 | Southern Miss (8-5,6-2) | 34 | at | Louisiana Tech | 27 | 2OT | ||
| 10/28/2017 | Louisiana Tech | 42 | at | Rice (1-11,1-7) | 28 | |||
| 11/4/2017 | North Texas (9-5,7-2) | 24 | at | Louisiana Tech | 23 | |||
| 11/11/2017 | Florida Atlantic (11-3,9-0) | 48 | at | Louisiana Tech | 23 | |||
| 11/18/2017 | Louisiana Tech | 42 | at | UTEP (0-12,0-8) | 21 | |||
| 11/25/2017 | Texas-San Antonio (6-5,3-5) | 6 | at | Louisiana Tech | 20 | |||
| 12/20/2017 | Louisiana Tech | 51 | vs | SMU (7-6) | 10 | Frisco Bowl (Frisco TX) | vs AAC |
| vs Louisiana Tech | vs Other Opponents | Louisiana Tech compared to OOs | |
| Record: | 6-7 | 76-75 | |
| Points Scored: | 25.38 | 27.23 | 1.85 |
| Points Allowed: | 30.46 | 27.49 | 2.97 |
| Margin: | -5.08 | -0.26 | 4.82 |
| Total Points: | 55.84 | 54.72 | 1.12 |