| 8/31/2017 | Austin Peay (8-4) | 14 | at | Cincinnati | 26 | OVC (1AA) | ||
| 9/9/2017 | Cincinnati | 14 | at | Michigan (8-5) | 36 | at B10 | ||
| 9/16/2017 | Cincinnati | 21 | at | Miami-Ohio (5-7) | 17 | at MAC | ||
| 9/23/2017 | Cincinnati | 32 | at | Navy (7-6,4-4) | 42 | |||
| 9/30/2017 | Marshall (8-5) | 38 | at | Cincinnati | 21 | CUSA | ||
| 10/7/2017 | UCF (13-0,9-0) | 51 | at | Cincinnati | 23 | |||
| 10/14/2017 | Cincinnati | 3 | at | South Florida (10-2,6-2) | 33 | |||
| 10/21/2017 | SMU (7-6,4-4) | 31 | at | Cincinnati | 28 | OT | ||
| 11/4/2017 | Cincinnati | 17 | at | Tulane (5-7,3-5) | 16 | |||
| 11/10/2017 | Temple (7-6,4-4) | 35 | at | Cincinnati | 24 | |||
| 11/18/2017 | Cincinnati | 20 | at | East Carolina (3-9,2-6) | 48 | |||
| 11/25/2017 | Connecticut (3-9,2-6) | 21 | at | Cincinnati | 22 |
| vs Cincinnati | vs Other Opponents | Cincinnati compared to OOs | |
| Record: | 8-4 | 76-62 | |
| Points Scored: | 31.83 | 29.89 | -1.94 |
| Points Allowed: | 20.92 | 28.62 | -7.70 |
| Margin: | 10.91 | 1.27 | -9.64 |
| Total Points: | 52.75 | 58.51 | -5.76 |