| 9/2/2017 | Hampton (6-5) | 0 | at | Ohio | 59 | MEAC (1AA) | ||
| 9/8/2017 | Ohio | 21 | at | Purdue (7-6) | 44 | at B10 | ||
| 9/16/2017 | Kansas (1-11) | 30 | at | Ohio | 42 | B12 | ||
| 9/23/2017 | Ohio | 27 | at | Eastern Michigan (5-7,3-5) | 20 | 2OT | ||
| 9/30/2017 | Ohio | 58 | at | Massachusetts (4-8) | 50 | at Ind | ||
| 10/7/2017 | Central Michigan (8-5,6-2) | 26 | at | Ohio | 23 | |||
| 10/14/2017 | Ohio | 48 | at | Bowling Green (2-10,2-6) | 30 | |||
| 10/21/2017 | Kent State (2-10,1-7) | 3 | at | Ohio | 48 | |||
| 10/31/2017 | Miami-Ohio (5-7,4-4) | 28 | at | Ohio | 45 | |||
| 11/8/2017 | Toledo (11-3,8-1) | 10 | at | Ohio | 38 | |||
| 11/14/2017 | Ohio | 34 | at | Akron (7-7,6-3) | 37 | |||
| 11/24/2017 | Ohio | 24 | at | Buffalo (6-6,4-4) | 31 | |||
| 12/22/2017 | UAB (8-5) | 6 | vs | Ohio | 41 | Bahamas Bowl (Nassau NP) | CUSA |
| vs Ohio | vs Other Opponents | Ohio compared to OOs | |
| Record: | 4-9 | 68-81 | |
| Points Scored: | 24.23 | 25.47 | 1.24 |
| Points Allowed: | 39.08 | 27.51 | 11.57 |
| Margin: | -14.85 | -2.04 | 12.81 |
| Total Points: | 63.31 | 52.98 | 10.33 |