| 9/2/2017 | North Carolina State (9-4) | 28 | vs | South Carolina | 35 | Charlotte NC | ACC | |
| 9/9/2017 | South Carolina | 31 | at | Missouri (7-6,4-4) | 13 | |||
| 9/16/2017 | Kentucky (7-6,4-4) | 23 | at | South Carolina | 13 | |||
| 9/23/2017 | Louisiana Tech (7-6) | 16 | at | South Carolina | 17 | CUSA | ||
| 9/30/2017 | South Carolina | 17 | at | Texas A&M (7-6,4-4) | 24 | |||
| 10/7/2017 | Arkansas (4-8,1-7) | 22 | at | South Carolina | 48 | |||
| 10/14/2017 | South Carolina | 15 | at | Tennessee (4-8,0-8) | 9 | |||
| 10/28/2017 | Vanderbilt (5-7,1-7) | 27 | at | South Carolina | 34 | |||
| 11/4/2017 | South Carolina | 10 | at | Georgia (13-2,8-2) | 24 | |||
| 11/11/2017 | Florida (4-7,3-5) | 20 | at | South Carolina | 28 | |||
| 11/18/2017 | Wofford (10-3) | 10 | at | South Carolina | 31 | SoCon (1AA) | ||
| 11/25/2017 | Clemson (12-2) | 34 | at | South Carolina | 10 | ACC | ||
| 1/1/2018 | Michigan (8-5) | 19 | vs | South Carolina | 26 | Outback Bowl (Tampa FL) | B10 |
| vs South Carolina | vs Other Opponents | South Carolina compared to OOs | |
| Record: | 4-9 | 93-61 | |
| Points Scored: | 20.69 | 29.68 | 8.99 |
| Points Allowed: | 24.23 | 25.68 | -1.45 |
| Margin: | -3.54 | 4.00 | 7.54 |
| Total Points: | 44.92 | 55.36 | -10.44 |