| 9/2/2017 | South Alabama | 27 | at | Mississippi (6-6) | 47 | at SEC | ||
| 9/8/2017 | Oklahoma State (10-3) | 44 | at | South Alabama | 7 | B12 | ||
| 9/16/2017 | Alabama A&M (4-7) | 0 | at | South Alabama | 45 | SWAC (1AA) | ||
| 9/23/2017 | Idaho (4-8,3-5) | 29 | at | South Alabama | 23 | 2OT | ||
| 9/30/2017 | South Alabama | 16 | at | Louisiana Tech (7-6) | 34 | at CUSA | ||
| 10/11/2017 | South Alabama | 19 | at | Troy (11-2,7-1) | 8 | |||
| 10/21/2017 | UL Monroe (4-8,4-4) | 23 | at | South Alabama | 33 | |||
| 10/26/2017 | South Alabama | 13 | at | Georgia State (7-5,5-3) | 21 | |||
| 11/4/2017 | UL Lafayette (5-7,4-4) | 19 | at | South Alabama | 14 | |||
| 11/11/2017 | Arkansas State (7-5,6-2) | 19 | at | South Alabama | 24 | |||
| 11/18/2017 | South Alabama | 0 | at | Georgia Southern (2-10,2-6) | 52 | |||
| 12/2/2017 | South Alabama | 17 | at | New Mexico State (7-6,4-4) | 22 |
| vs South Alabama | vs Other Opponents | South Alabama compared to OOs | |
| Record: | 8-4 | 66-69 | |
| Points Scored: | 26.50 | 29.52 | 3.02 |
| Points Allowed: | 19.83 | 30.22 | -10.39 |
| Margin: | 6.67 | -0.70 | -7.37 |
| Total Points: | 46.33 | 59.74 | -13.41 |