| 8/31/2017 | Eastern Illinois | 22 | at | Indiana State (0-11) | 20 | at MVC | ||
| 9/9/2017 | Eastern Illinois | 10 | at | Northern Illinois (8-5) | 38 | at MAC | ||
| 9/16/2017 | Illinois State (6-5) | 44 | at | Eastern Illinois | 13 | MVC | ||
| 9/23/2017 | SE Missouri State (3-8,3-5) | 16 | at | Eastern Illinois | 19 | |||
| 9/30/2017 | Eastern Illinois | 19 | at | Tennessee State (6-5,2-5) | 16 | 2OT | ||
| 10/7/2017 | Tennessee Tech (1-10,1-7) | 23 | at | Eastern Illinois | 24 | |||
| 10/14/2017 | Eastern Illinois | 27 | at | Murray State (3-8,2-5) | 24 | 2OT | ||
| 10/21/2017 | Jacksonville State (10-2,8-0) | 30 | at | Eastern Illinois | 14 | |||
| 10/28/2017 | Eastern Illinois | 10 | at | Tennessee-Martin (6-5,4-4) | 27 | |||
| 11/4/2017 | Eastern Kentucky (4-7,3-5) | 20 | at | Eastern Illinois | 23 | OT | ||
| 11/18/2017 | Eastern Illinois | 13 | at | Austin Peay (8-4,7-1) | 28 |
| vs Eastern Illinois | vs Other Opponents | Eastern Illinois compared to OOs | |
| Record: | 5-6 | 50-64 | |
| Points Scored: | 26.00 | 22.37 | -3.63 |
| Points Allowed: | 17.64 | 24.81 | -7.17 |
| Margin: | 8.36 | -2.44 | -10.80 |
| Total Points: | 43.64 | 47.18 | -3.54 |