| 8/26/2017 | Chattanooga (3-8) | 13 | vs | Jacksonville State | 27 | Montgomery AL | SoCon | |
| 9/9/2017 | Jacksonville State | 10 | at | Georgia Tech (5-6) | 37 | at ACC | ||
| 9/23/2017 | Liberty (6-5) | 10 | at | Jacksonville State | 31 | BigS | ||
| 9/30/2017 | Jacksonville State | 34 | at | Tennessee Tech (1-10,1-7) | 7 | |||
| 10/7/2017 | Jacksonville State | 34 | at | Austin Peay (8-4,7-1) | 14 | |||
| 10/14/2017 | Eastern Kentucky (4-7,3-5) | 25 | at | Jacksonville State | 41 | |||
| 10/21/2017 | Jacksonville State | 30 | at | Eastern Illinois (6-5,5-3) | 14 | |||
| 10/28/2017 | SE Missouri State (3-8,3-5) | 7 | at | Jacksonville State | 23 | |||
| 11/4/2017 | Murray State (3-8,2-5) | 23 | at | Jacksonville State | 59 | |||
| 11/11/2017 | Jacksonville State | 14 | at | Tennessee-Martin (6-5,4-4) | 7 | |||
| 11/16/2017 | Tennessee State (6-5,2-5) | 6 | at | Jacksonville State | 36 | |||
| 12/2/2017 | Kennesaw St (12-2) | 17 | at | Jacksonville State | 7 | 1AA Playoff Round 2 | BigS |
| vs Jacksonville State | vs Other Opponents | Jacksonville State compared to OOs | |
| Record: | 2-10 | 61-63 | |
| Points Scored: | 15.00 | 23.92 | 8.92 |
| Points Allowed: | 28.83 | 23.52 | 5.31 |
| Margin: | -13.83 | 0.40 | 14.23 |
| Total Points: | 43.83 | 47.44 | -3.61 |