| 9/2/2017 | Miami-Ohio (5-7) | 26 | at | Marshall | 31 | MAC | ||
| 9/9/2017 | Marshall | 20 | at | North Carolina State (9-4) | 37 | at ACC | ||
| 9/16/2017 | Kent State (2-10) | 0 | at | Marshall | 21 | MAC | ||
| 9/30/2017 | Marshall | 38 | at | Cincinnati (4-8) | 21 | at AAC | ||
| 10/7/2017 | Marshall | 14 | at | UNC-Charlotte (1-11,1-7) | 3 | |||
| 10/14/2017 | Old Dominion (5-7,3-5) | 3 | at | Marshall | 35 | |||
| 10/20/2017 | Marshall | 38 | at | Middle Tenn State (7-6,4-4) | 10 | |||
| 10/28/2017 | Florida Intl (8-5,5-3) | 41 | at | Marshall | 30 | |||
| 11/3/2017 | Marshall | 25 | at | Florida Atlantic (11-3,9-0) | 30 | |||
| 11/11/2017 | Western Kentucky (6-7,4-4) | 23 | at | Marshall | 30 | |||
| 11/18/2017 | Marshall | 7 | at | Texas-San Antonio (6-5,3-5) | 9 | |||
| 11/25/2017 | Southern Miss (8-5,6-2) | 28 | at | Marshall | 27 | |||
| 12/16/2017 | Marshall | 31 | vs | Colorado State (7-6) | 28 | New Mexico Bowl (Albuquerque NM) | vs MW |
| vs Marshall | vs Other Opponents | Marshall compared to OOs | |
| Record: | 5-8 | 74-76 | |
| Points Scored: | 19.92 | 26.07 | 6.15 |
| Points Allowed: | 26.69 | 27.13 | -0.44 |
| Margin: | -6.77 | -1.06 | 5.71 |
| Total Points: | 46.61 | 53.20 | -6.59 |