| 9/1/2016 | Appalachian State | 13 | at | Tennessee | 20 | OT | SBC | |
| South Carolina | 13 | at | Vanderbilt | 10 | ||||
| 9/3/2016 | Southern California | 6 | vs | Alabama | 52 | Arlington TX | vs P12 | |
| Louisiana Tech | 20 | at | Arkansas | 21 | CUSA | |||
| Clemson | 19 | at | Auburn | 13 | ACC | |||
| Massachusetts | 7 | at | Florida | 24 | MAC | |||
| North Carolina | 24 | vs | Georgia | 33 | Atlanta GA | vs ACC | ||
| Southern Miss | 44 | at | Kentucky | 35 | CUSA | |||
| South Alabama | 21 | at | Mississippi State | 20 | SBC | |||
| UCLA | 24 | at | Texas A&M | 31 | OT | P12 | ||
| Missouri | 11 | at | West Virginia | 26 | @ B12 | |||
| LSU | 14 | vs | Wisconsin | 16 | Green Bay WI | vs B10 | ||
| 9/5/2016 | Mississippi | 34 | vs | Florida State | 45 | Orlando FL | vs ACC | |
| 9/10/2016 | Western Kentucky | 10 | at | Alabama | 38 | CUSA | ||
| Arkansas State | 14 | at | Auburn | 51 | SBC | |||
| Kentucky | 7 | at | Florida | 45 | ||||
| Nicholls State | 24 | at | Georgia | 26 | SLC (1AA) | |||
| Jacksonville State | 13 | at | LSU | 34 | OVC (1AA) | |||
| Wofford | 13 | at | Mississippi | 38 | SoCon (1AA) | |||
| South Carolina | 14 | at | Mississippi State | 27 | ||||
| Eastern Michigan | 21 | at | Missouri | 61 | MAC | |||
| Arkansas | 41 | at | TCU | 38 | 2OT | @ B12 | ||
| Virginia Tech | 24 | vs | Tennessee | 45 | Bristol TN | vs ACC | ||
| Prairie View | 0 | at | Texas A&M | 67 | SWAC (1AA) | |||
| Middle Tenn State | 24 | at | Vanderbilt | 47 | CUSA | |||
| 9/17/2016 | Texas State | 3 | at | Arkansas | 42 | SBC | ||
| Texas A&M | 29 | at | Auburn | 16 | ||||
| North Texas | 0 | at | Florida | 32 | CUSA | |||
| Vanderbilt | 7 | at | Georgia Tech | 38 | @ ACC | |||
| New Mexico State | 42 | at | Kentucky | 62 | SBC | |||
| Mississippi State | 20 | at | LSU | 23 | ||||
| Alabama | 48 | at | Mississippi | 43 | ||||
| Georgia | 28 | at | Missouri | 27 | ||||
| East Carolina | 15 | at | South Carolina | 20 | AAC | |||
| Ohio | 19 | at | Tennessee | 28 | MAC | |||
| 9/24/2016 | Kent State | 0 | at | Alabama | 48 | MAC | ||
| LSU | 13 | at | Auburn | 18 | ||||
| South Carolina | 10 | at | Kentucky | 17 | ||||
| Mississippi State | 47 | vs | Massachusetts | 35 | Foxboro MA | vs MAC | ||
| Georgia | 14 | at | Mississippi | 45 | ||||
| Delaware State | 0 | at | Missouri | 79 | MEAC (1AA) | |||
| Florida | 28 | at | Tennessee | 38 | ||||
| Arkansas | 24 | vs | Texas A&M | 45 | Arlington TX | |||
| Vanderbilt | 31 | at | Western Kentucky | 30 | OT | @ CUSA | ||
| 10/1/2016 | Kentucky | 6 | at | Alabama | 34 | |||
| Alcorn State | 10 | vs | Arkansas | 52 | Little Rock AR | vs SWAC (1AA) | ||
| UL Monroe | 7 | at | Auburn | 58 | SBC | |||
| Tennessee | 34 | at | Georgia | 31 | ||||
| Missouri | 7 | at | LSU | 42 | ||||
| Memphis | 28 | at | Mississippi | 48 | AAC | |||
| Texas A&M | 24 | at | South Carolina | 13 | ||||
| Florida | 13 | at | Vanderbilt | 6 | ||||
| 10/8/2016 | Alabama | 49 | at | Arkansas | 30 | |||
| LSU | vs | Florida | Cancelled WX | |||||
| Vanderbilt | 13 | at | Kentucky | 20 | ||||
| Auburn | 38 | at | Mississippi State | 14 | ||||
| Tennessee | 38 | at | Texas A&M | 45 | 2OT | |||
| 10/9/2016 | Georgia | 28 | at | South Carolina | 14 | |||
| 10/14/2016 | Mississippi State | 21 | at | BYU | 28 | @ Ind | ||
| 10/15/2016 | Mississippi | 30 | at | Arkansas | 34 | |||
| Missouri | 14 | at | Florida | 40 | ||||
| Vanderbilt | 17 | at | Georgia | 16 | ||||
| Southern Miss | 10 | at | LSU | 45 | CUSA | |||
| Alabama | 49 | at | Tennessee | 10 | ||||
| 10/22/2016 | Texas A&M | 14 | at | Alabama | 33 | |||
| Arkansas | 3 | at | Auburn | 56 | ||||
| Mississippi State | 38 | at | Kentucky | 40 | ||||
| Mississippi | 21 | at | LSU | 38 | ||||
| Middle Tenn State | 51 | at | Missouri | 45 | CUSA | |||
| Massachusetts | 28 | at | South Carolina | 34 | MAC | |||
| Tennessee State | 17 | at | Vanderbilt | 35 | OVC (1AA) | |||
| 10/29/2016 | Florida | 24 | vs | Georgia | 10 | Jacksonville FL | ||
| Auburn | 40 | at | Mississippi | 29 | ||||
| Samford | 41 | at | Mississippi State | 56 | SoCon (1AA) | |||
| Kentucky | 35 | at | Missouri | 21 | ||||
| Tennessee | 21 | at | South Carolina | 24 | ||||
| New Mexico State | 10 | at | Texas A&M | 52 | SBC | |||
| 11/5/2016 | Florida | 10 | at | Arkansas | 31 | |||
| Vanderbilt | 16 | at | Auburn | 23 | ||||
| Georgia | 27 | at | Kentucky | 24 | ||||
| Alabama | 10 | at | LSU | 0 | ||||
| Georgia Southern | 27 | at | Mississippi | 37 | SBC | |||
| Texas A&M | 28 | at | Mississippi State | 35 | ||||
| Missouri | 21 | at | South Carolina | 31 | ||||
| Tennessee Tech | 0 | at | Tennessee | 55 | OVC (1AA) | |||
| 11/12/2016 | Mississippi State | 3 | at | Alabama | 51 | |||
| LSU | 38 | at | Arkansas | 10 | ||||
| South Carolina | 7 | at | Florida | 20 | ||||
| Auburn | 7 | at | Georgia | 13 | ||||
| Vanderbilt | 17 | at | Missouri | 26 | ||||
| Kentucky | 36 | at | Tennessee | 49 | ||||
| Mississippi | 29 | at | Texas A&M | 28 | ||||
| 11/19/2016 | Chattanooga | 3 | at | Alabama | 31 | SoCon (1AA) | ||
| Alabama A&M | 0 | at | Auburn | 55 | SWAC (1AA) | |||
| UL Lafayette | 21 | at | Georgia | 35 | SBC | |||
| Austin Peay | 13 | at | Kentucky | 49 | OVC (1AA) | |||
| Florida | 16 | at | LSU | 10 | ||||
| Arkansas | 58 | at | Mississippi State | 42 | ||||
| Western Carolina | 31 | at | South Carolina | 44 | SoCon (1AA) | |||
| Missouri | 37 | at | Tennessee | 63 | ||||
| Texas-San Antonio | 10 | at | Texas A&M | 23 | CUSA | |||
| Mississippi | 17 | at | Vanderbilt | 38 | ||||
| 11/24/2016 | LSU | 54 | at | Texas A&M | 39 | |||
| 11/25/2016 | Arkansas | 24 | at | Missouri | 28 | |||
| 11/26/2016 | Auburn | 12 | at | Alabama | 30 | |||
| South Carolina | 7 | at | Clemson | 56 | @ ACC | |||
| Florida | 13 | at | Florida State | 31 | @ ACC | |||
| Georgia Tech | 28 | at | Georgia | 27 | ACC | |||
| Kentucky | 41 | at | Louisville | 38 | @ ACC | |||
| Mississippi State | 55 | at | Mississippi | 20 | ||||
| Tennessee | 34 | at | Vanderbilt | 45 | ||||
| 12/3/2016 | Alabama | 54 | vs | Florida | 16 | Atlanta GA | ||
| 12/26/2016 | Miami-Ohio | 16 | vs | Mississippi State | 17 | St. Petersburg Bowl | vs MAC | |
| North Carolina State | 41 | vs | Vanderbilt | 17 | Independence Bowl (Shreveport LA) | vs ACC | ||
| 12/28/2016 | Texas A&M | 28 | vs | Kansas State | 33 | Texas Bowl (Houston TX) | vs B12 | |
| 12/29/2016 | South Florida | 46 | vs | South Carolina | 39 | OT | Birmingham Bowl | vs AAC |
| Arkansas | 24 | vs | Virginia Tech | 35 | Belk Bowl (Charlotte NC) | vs ACC | ||
| 12/30/2016 | Georgia | 31 | vs | TCU | 23 | Liberty Bowl (Memphis TN) | vs B12 | |
| Nebraska | 24 | vs | Tennessee | 38 | Music City Bowl (Nashville TN) | vs B10 | ||
| 12/31/2016 | Washington | 7 | vs | Alabama | 24 | Peach Bowl (Atlanta GA - 1A Semifinal) | vs P12 | |
| Georgia Tech | 33 | vs | Kentucky | 18 | Taxslayer Bowl (Jacksonville FL) | vs ACC | ||
| LSU | 29 | vs | Louisville | 9 | Citrus Bowl (Orlando FL) | vs ACC | ||
| 1/2/2017 | Florida | 30 | vs | Iowa | 3 | Outback Bowl (Tampa FL) | vs B10 | |
| Auburn | 19 | vs | Oklahoma | 35 | Sugar Bowl (New Orleans LA) | vs B12 | ||
| 1/9/2017 | Clemson | 35 | vs | Alabama | 31 | 1A Championship (Tampa FL) | vs ACC |