| 9/3/2016 | Western Carolina | 7 | at | East Carolina (3-9) | 52 | at AAC | ||
| 9/10/2016 | Gardner-Webb (5-6) | 14 | at | Western Carolina | 44 | BigS | ||
| 9/17/2016 | Western Carolina | 31 | at | East Tennessee St (5-6) | 34 | at IndFCS | ||
| 10/1/2016 | The Citadel (10-2,7-1) | 37 | at | Western Carolina | 14 | |||
| 10/8/2016 | Wofford (10-4,6-2) | 31 | at | Western Carolina | 19 | |||
| 10/15/2016 | Western Carolina | 24 | at | Mercer (6-5,3-4) | 38 | |||
| 10/22/2016 | Western Carolina | 17 | at | Samford (7-5,5-2) | 30 | |||
| 10/29/2016 | Chattanooga (9-4,5-2) | 38 | at | Western Carolina | 25 | |||
| 11/5/2016 | VMI (3-8,0-7) | 29 | at | Western Carolina | 32 | |||
| 11/12/2016 | Western Carolina | 21 | at | Furman (3-8,2-5) | 49 | |||
| 11/19/2016 | Western Carolina | 31 | at | South Carolina (6-7) | 44 | at SEC |
| vs Western Carolina | vs Other Opponents | Western Carolina compared to OOs | |
| Record: | 9-2 | 58-62 | |
| Points Scored: | 36.00 | 25.24 | -10.76 |
| Points Allowed: | 24.09 | 25.49 | -1.40 |
| Margin: | 11.91 | -0.25 | -12.16 |
| Total Points: | 60.09 | 50.73 | 9.36 |