| 9/1/2016 | William & Mary (5-6) | 14 | at | North Carolina State | 48 | CAAF (1AA) | ||
| 9/10/2016 | North Carolina State | 30 | at | East Carolina (3-9) | 33 | at AAC | ||
| 9/17/2016 | Old Dominion (10-3) | 22 | at | North Carolina State | 49 | CUSA | ||
| 10/1/2016 | Wake Forest (7-6,3-5) | 16 | at | North Carolina State | 33 | |||
| 10/8/2016 | Notre Dame (4-8) | 3 | at | North Carolina State | 10 | ND | ||
| 10/15/2016 | North Carolina State | 17 | at | Clemson (14-1,8-1) | 24 | OT | ||
| 10/22/2016 | North Carolina State | 13 | at | Louisville (9-4,7-1) | 54 | |||
| 10/29/2016 | Boston College (7-6,2-6) | 21 | at | North Carolina State | 14 | |||
| 11/5/2016 | Florida State (10-3,5-3) | 24 | at | North Carolina State | 20 | |||
| 11/12/2016 | North Carolina State | 35 | at | Syracuse (4-8,2-6) | 20 | |||
| 11/19/2016 | Miami-Florida (9-4,5-3) | 27 | at | North Carolina State | 13 | |||
| 11/25/2016 | North Carolina State | 28 | at | North Carolina (8-5,5-3) | 21 | |||
| 12/26/2016 | North Carolina State | 41 | vs | Vanderbilt (6-7) | 17 | Independence Bowl (Shreveport LA) | vs SEC |
| vs North Carolina State | vs Other Opponents | North Carolina State compared to OOs | |
| Record: | 6-7 | 90-63 | |
| Points Scored: | 22.77 | 30.71 | 7.94 |
| Points Allowed: | 27.00 | 25.40 | 1.60 |
| Margin: | -4.23 | 5.31 | 9.54 |
| Total Points: | 49.77 | 56.11 | -6.34 |