| 9/3/2016 | Fresno State (1-11) | 10 | at | Nebraska | 43 | MW | ||
| 9/10/2016 | Wyoming (8-6) | 17 | at | Nebraska | 52 | MW | ||
| 9/17/2016 | Oregon (4-8) | 32 | at | Nebraska | 35 | P12 | ||
| 9/24/2016 | Nebraska | 24 | at | Northwestern (7-6,5-4) | 13 | |||
| 10/1/2016 | Illinois (3-9,2-7) | 16 | at | Nebraska | 31 | |||
| 10/15/2016 | Nebraska | 27 | at | Indiana (6-7,4-5) | 22 | |||
| 10/22/2016 | Purdue (3-9,1-8) | 14 | at | Nebraska | 27 | |||
| 10/29/2016 | Nebraska | 17 | at | Wisconsin (11-3,7-3) | 23 | OT | ||
| 11/5/2016 | Nebraska | 3 | at | Ohio State (11-2,8-1) | 62 | |||
| 11/12/2016 | Minnesota (9-4,5-4) | 17 | at | Nebraska | 24 | |||
| 11/19/2016 | Maryland (6-7,3-6) | 7 | at | Nebraska | 28 | |||
| 11/25/2016 | Nebraska | 10 | at | Iowa (8-5,6-3) | 40 | |||
| 12/30/2016 | Nebraska | 24 | vs | Tennessee (9-4) | 38 | Music City Bowl (Nashville TN) | vs SEC |
| vs Nebraska | vs Other Opponents | Nebraska compared to OOs | |
| Record: | 4-9 | 82-72 | |
| Points Scored: | 23.92 | 28.93 | 5.01 |
| Points Allowed: | 26.54 | 27.24 | -0.70 |
| Margin: | -2.62 | 1.69 | 4.31 |
| Total Points: | 50.46 | 56.17 | -5.71 |