| 9/3/2016 | SE Missouri State (3-8) | 17 | at | Memphis | 35 | OVC (1AA) | ||
| 9/17/2016 | Kansas (2-10) | 7 | at | Memphis | 43 | B12 | ||
| 9/24/2016 | Bowling Green (4-8) | 3 | at | Memphis | 77 | MAC | ||
| 10/1/2016 | Memphis | 28 | at | Mississippi (5-7) | 48 | at SEC | ||
| 10/6/2016 | Temple (10-4,8-1) | 27 | at | Memphis | 34 | |||
| 10/14/2016 | Memphis | 24 | at | Tulane (4-8,1-7) | 14 | |||
| 10/22/2016 | Memphis | 28 | at | Navy (9-5,7-2) | 42 | |||
| 10/29/2016 | Tulsa (10-3,6-2) | 59 | at | Memphis | 30 | |||
| 11/5/2016 | Memphis | 51 | at | SMU (5-7,3-5) | 7 | |||
| 11/12/2016 | South Florida (11-2,7-1) | 49 | at | Memphis | 42 | |||
| 11/18/2016 | Memphis | 34 | at | Cincinnati (4-8,1-7) | 7 | |||
| 11/25/2016 | Houston (9-4,5-3) | 44 | at | Memphis | 48 | |||
| 12/20/2016 | Memphis | 31 | vs | Western Kentucky (11-3) | 51 | Boca Raton Bowl | vs CUSA |
| vs Memphis | vs Other Opponents | Memphis compared to OOs | |
| Record: | 5-8 | 82-69 | |
| Points Scored: | 28.85 | 32.10 | 3.25 |
| Points Allowed: | 38.85 | 28.54 | 10.31 |
| Margin: | -10.00 | 3.56 | 13.56 |
| Total Points: | 67.70 | 60.64 | 7.06 |