| 9/3/2016 | South Dakota State (9-4) | 41 | at | TCU | 59 | MVC (1AA) | ||
| 9/10/2016 | Arkansas (7-6) | 41 | at | TCU | 38 | 2OT | SEC | |
| 9/17/2016 | Iowa State (3-9,2-7) | 20 | at | TCU | 41 | |||
| 9/23/2016 | TCU | 33 | at | SMU (5-7) | 3 | at AAC | ||
| 10/1/2016 | Oklahoma (11-2,9-0) | 52 | at | TCU | 46 | |||
| 10/8/2016 | TCU | 24 | at | Kansas (2-10,1-8) | 23 | |||
| 10/22/2016 | TCU | 10 | at | West Virginia (10-3,7-2) | 34 | |||
| 10/29/2016 | Texas Tech (5-7,3-6) | 27 | at | TCU | 24 | |||
| 11/5/2016 | TCU | 62 | at | Baylor (7-6,3-6) | 22 | |||
| 11/19/2016 | Oklahoma State (10-3,7-2) | 31 | at | TCU | 6 | |||
| 11/25/2016 | TCU | 31 | at | Texas (5-7,3-6) | 9 | |||
| 12/3/2016 | Kansas State (9-4,6-3) | 30 | at | TCU | 6 | |||
| 12/30/2016 | Georgia (8-5) | 31 | vs | TCU | 23 | Liberty Bowl (Memphis TN) | SEC |
| vs TCU | vs Other Opponents | TCU compared to OOs | |
| Record: | 7-6 | 84-67 | |
| Points Scored: | 28.00 | 32.72 | 4.72 |
| Points Allowed: | 31.00 | 29.97 | 1.03 |
| Margin: | -3.00 | 2.75 | 5.75 |
| Total Points: | 59.00 | 62.69 | -3.69 |