| 9/4/2016 | Alcorn State | at | Bethune-Cookman (4-6) | Cancelled | at MEAC | |||
| 9/10/2016 | Alabama State (4-7,3-6) | 18 | at | Alcorn State | 21 | |||
| 9/15/2016 | Ark Pine Bluff (1-10,1-8) | 45 | at | Alcorn State | 43 | |||
| 9/24/2016 | Alcorn State | 18 | at | Grambling (11-1,10-0) | 43 | |||
| 10/1/2016 | Alcorn State | 10 | vs | Arkansas (7-6) | 52 | Little Rock AR | vs SEC | |
| 10/8/2016 | Alcorn State | 42 | at | Alabama A&M (4-7,4-5) | 19 | |||
| 10/15/2016 | Texas Southern (4-7,4-5) | 20 | at | Alcorn State | 23 | |||
| 10/29/2016 | Southern (8-3,8-1) | 41 | at | Alcorn State | 33 | |||
| 11/5/2016 | Alcorn State | 27 | at | Prairie View (7-4,7-2) | 31 | |||
| 11/12/2016 | Alcorn State | 61 | at | Mississippi Valley State (1-10,1-8) | 7 | |||
| 11/19/2016 | Jackson State (3-8,3-6) | 16 | at | Alcorn State | 35 | |||
| 12/3/2016 | Grambling (11-1,10-0) | 27 | vs | Alcorn State | 20 |
| vs Alcorn State | vs Other Opponents | Alcorn State compared to OOs | |
| Record: | 6-5 | 57-65 | |
| Points Scored: | 29.00 | 27.79 | -1.21 |
| Points Allowed: | 30.27 | 30.16 | 0.11 |
| Margin: | -1.27 | -2.37 | -1.10 |
| Total Points: | 59.27 | 57.95 | 1.32 |