| 9/3/2015 | North Carolina | 13 | vs | South Carolina | 17 | Charlotte NC | vs ACC | |
| Western Kentucky | 14 | at | Vanderbilt | 12 | CUSA | |||
| 9/5/2015 | Wisconsin | 17 | vs | Alabama | 35 | Arlington TX | vs B10 | |
| UTEP | 13 | at | Arkansas | 48 | CUSA | |||
| Louisville | 24 | vs | Auburn | 31 | Atlanta GA | vs ACC | ||
| New Mexico State | 13 | at | Florida | 61 | SBC | |||
| UL Monroe | 14 | at | Georgia | 51 | SBC | |||
| UL Lafayette | 33 | at | Kentucky | 40 | SBC | |||
| McNeese State | at | LSU | CCD | SLC (1AA) | ||||
| Tennessee-Martin | 3 | at | Mississippi | 76 | OVC (1AA) | |||
| SE Missouri State | 3 | at | Missouri | 34 | OVC (1AA) | |||
| Mississippi State | 34 | at | Southern Miss | 16 | @ CUSA | |||
| Bowling Green | 30 | vs | Tennessee | 59 | Nashville TN | vs MAC | ||
| Arizona State | 17 | vs | Texas A&M | 38 | Houston TX | vs P12 | ||
| 9/12/2015 | Middle Tenn State | 10 | at | Alabama | 37 | CUSA | ||
| Toledo | 16 | vs | Arkansas | 12 | Little Rock AR | vs MAC | ||
| Missouri | 27 | at | Arkansas State | 20 | @ SBC | |||
| Jacksonville State | 20 | at | Auburn | 27 | OT | OVC (1AA) | ||
| East Carolina | 24 | at | Florida | 31 | AAC | |||
| Fresno State | 21 | at | Mississippi | 73 | MW | |||
| LSU | 21 | at | Mississippi State | 19 | ||||
| Kentucky | 26 | at | South Carolina | 22 | ||||
| Oklahoma | 31 | at | Tennessee | 24 | 2OT | B12 | ||
| Ball State | 23 | at | Texas A&M | 56 | MAC | |||
| Georgia | 31 | at | Vanderbilt | 14 | ||||
| 9/19/2015 | Mississippi | 43 | at | Alabama | 37 | |||
| Texas Tech | 35 | at | Arkansas | 24 | B12 | |||
| South Carolina | 20 | at | Georgia | 52 | ||||
| Florida | 14 | at | Kentucky | 9 | ||||
| Auburn | 21 | at | LSU | 45 | ||||
| Northwestern State | 13 | at | Mississippi State | 62 | SLC (1AA) | |||
| Connecticut | 6 | at | Missouri | 9 | AAC | |||
| Western Carolina | 10 | at | Tennessee | 55 | SoCon (1AA) | |||
| Nevada | 27 | at | Texas A&M | 44 | MW | |||
| Austin Peay | 7 | at | Vanderbilt | 47 | OVC (1AA) | |||
| 9/26/2015 | UL Monroe | 0 | at | Alabama | 34 | SBC | ||
| Mississippi State | 17 | at | Auburn | 9 | ||||
| Tennessee | 27 | at | Florida | 28 | ||||
| Southern | 6 | at | Georgia | 48 | SWAC (1AA) | |||
| Missouri | 13 | at | Kentucky | 21 | ||||
| Vanderbilt | 17 | at | Mississippi | 26 | ||||
| UCF | 14 | at | South Carolina | 31 | AAC | |||
| LSU | 34 | at | Syracuse | 24 | @ ACC | |||
| Arkansas | 21 | at | Texas A&M | 28 | OT | Arlington TX | ||
| 10/3/2015 | San Jose State | 21 | at | Auburn | 35 | MW | ||
| Mississippi | 10 | at | Florida | 38 | ||||
| Alabama | 38 | at | Georgia | 10 | ||||
| Eastern Kentucky | 27 | at | Kentucky | 34 | OT | OVC (1AA) | ||
| Eastern Michigan | 22 | at | LSU | 44 | MAC | |||
| Vanderbilt | 17 | at | Middle Tenn State | 13 | @ CUSA | |||
| South Carolina | 10 | at | Missouri | 24 | ||||
| Arkansas | 24 | at | Tennessee | 20 | ||||
| Mississippi State | 17 | at | Texas A&M | 30 | ||||
| 10/10/2015 | Arkansas | 14 | at | Alabama | 27 | |||
| New Mexico State | 3 | at | Mississippi | 52 | SBC | |||
| Troy | 17 | at | Mississippi State | 45 | SBC | |||
| Florida | 21 | at | Missouri | 3 | ||||
| LSU | 45 | at | South Carolina | 24 | Baton Rouge LA (SC home game) | |||
| Georgia | 31 | at | Tennessee | 38 | ||||
| 10/15/2015 | Auburn | 30 | at | Kentucky | 27 | |||
| 10/17/2015 | Missouri | 6 | at | Georgia | 9 | |||
| Florida | 28 | at | LSU | 35 | ||||
| Mississippi | 24 | at | Memphis | 37 | @ AAC | |||
| Louisiana Tech | 20 | at | Mississippi State | 45 | CUSA | |||
| Vanderbilt | 10 | at | South Carolina | 19 | ||||
| Alabama | 41 | at | Texas A&M | 23 | ||||
| 10/24/2015 | Tennessee | 14 | at | Alabama | 19 | |||
| Auburn | 46 | at | Arkansas | 54 | 4OT | |||
| Western Kentucky | 20 | at | LSU | 48 | CUSA | |||
| Texas A&M | 3 | at | Mississippi | 23 | ||||
| Kentucky | 16 | at | Mississippi State | 42 | ||||
| Missouri | 3 | at | Vanderbilt | 10 | ||||
| 10/31/2015 | Tennessee-Martin | 28 | at | Arkansas | 63 | OVC (1AA) | ||
| Mississippi | 27 | at | Auburn | 19 | ||||
| Georgia | 3 | vs | Florida | 27 | Jacksonville FL | |||
| Vanderbilt | 0 | at | Houston | 34 | @ AAC | |||
| Tennessee | 52 | at | Kentucky | 21 | ||||
| South Carolina | 28 | at | Texas A&M | 35 | ||||
| 11/5/2015 | Mississippi State | 31 | at | Missouri | 13 | |||
| 11/7/2015 | LSU | 16 | at | Alabama | 30 | |||
| Vanderbilt | 7 | at | Florida | 9 | ||||
| Kentucky | 3 | at | Georgia | 27 | ||||
| Arkansas | 53 | at | Mississippi | 52 | OT | |||
| South Carolina | 24 | at | Tennessee | 27 | ||||
| Auburn | 26 | at | Texas A&M | 10 | ||||
| 11/14/2015 | Georgia | 20 | at | Auburn | 13 | |||
| Arkansas | 31 | at | LSU | 14 | ||||
| Alabama | 31 | at | Mississippi State | 6 | ||||
| BYU | 16 | vs | Missouri | 20 | Kansas City MO | vs Ind | ||
| Florida | 24 | at | South Carolina | 14 | ||||
| North Texas | 0 | at | Tennessee | 24 | CUSA | |||
| Western Carolina | 17 | at | Texas A&M | 41 | SoCon (1AA) | |||
| Kentucky | 17 | at | Vanderbilt | 21 | ||||
| 11/21/2015 | Charleston Southern | 6 | at | Alabama | 56 | BigS (1AA) | ||
| Mississippi State | 51 | at | Arkansas | 50 | ||||
| Idaho | 34 | at | Auburn | 56 | SBC | |||
| Florida Atlantic | 14 | at | Florida | 20 | OT | CUSA | ||
| Georgia Southern | 17 | at | Georgia | 23 | OT | SBC | ||
| UNC-Charlotte | 10 | at | Kentucky | 58 | CUSA | |||
| LSU | 17 | at | Mississippi | 38 | ||||
| Tennessee | 19 | at | Missouri | 8 | ||||
| The Citadel | 23 | at | South Carolina | 22 | SoCon (1AA) | |||
| Texas A&M | 25 | at | Vanderbilt | 0 | ||||
| 11/27/2015 | Missouri | 3 | at | Arkansas | 28 | |||
| 11/28/2015 | Alabama | 29 | at | Auburn | 13 | |||
| Florida State | 27 | at | Florida | 2 | ACC | |||
| Georgia | 13 | at | Georgia Tech | 7 | @ ACC | |||
| Louisville | 38 | at | Kentucky | 24 | ACC | |||
| Texas A&M | 7 | at | LSU | 19 | ||||
| Mississippi | 38 | at | Mississippi State | 27 | ||||
| Clemson | 37 | at | South Carolina | 32 | ACC | |||
| Vanderbilt | 28 | at | Tennessee | 53 | ||||
| 12/5/2015 | Florida | 15 | vs | Alabama | 29 | SEC Championship (Atlanta GA) | ||
| 12/29/2015 | LSU | 56 | vs | Texas Tech | 27 | Texas Bowl (Houston TX) | vs B12 | |
| 12/30/2015 | Texas A&M | 21 | vs | Louisville | 27 | Music City Bowl (Nashville TN) | vs ACC | |
| Auburn | 31 | vs | Memphis | 10 | Birmingham Bowl (Birmingham AL) | vs AAC | ||
| North Carolina State | 28 | vs | Mississippi State | 51 | Belk Bowl (Charlotte NC) | vs ACC | ||
| 12/31/2015 | Michigan State | 0 | vs | Alabama | 38 | Cotton Bowl (Arlington TX) | vs B10 | |
| 1/1/2016 | Michigan | 41 | vs | Florida | 7 | Citrus Bowl (Orlando FL) | vs B10 | |
| Oklahoma State | 20 | vs | Mississippi | 48 | Sugar Bowl (New Orleans LA) | vs B12 | ||
| Northwestern | 6 | vs | Tennessee | 45 | Outback Bowl (Tampa FL) | vs B10 | ||
| 1/2/2016 | Kansas State | 23 | vs | Arkansas | 45 | Liberty Bowl (Memphis TN) | vs B12 | |
| Penn State | 17 | vs | Georgia | 24 | Taxslayer Bowl (Jacksonville FL) | vs B10 | ||
| 1/11/2016 | Alabama | 45 | vs | Clemson | 40 | CFP National Championship | vs ACC |