| 9/4/2015 | Rhode Island (1-10) | 0 | at | Syracuse | 47 | CAAF (1AA) | ||
| 9/12/2015 | Wake Forest (3-9,1-7) | 17 | at | Syracuse | 30 | |||
| 9/19/2015 | Central Michigan (7-6) | 27 | at | Syracuse | 30 | OT | MAC | |
| 9/26/2015 | LSU (9-3) | 34 | at | Syracuse | 24 | SEC | ||
| 10/10/2015 | Syracuse | 24 | at | South Florida (8-5) | 45 | at AAC | ||
| 10/17/2015 | Syracuse | 38 | at | Virginia (4-8,3-5) | 44 | 3OT | ||
| 10/24/2015 | Pittsburgh (8-5,6-2) | 23 | at | Syracuse | 20 | |||
| 10/31/2015 | Syracuse | 21 | at | Florida State (10-3,6-2) | 45 | |||
| 11/7/2015 | Syracuse | 17 | at | Louisville (8-5,5-3) | 41 | |||
| 11/14/2015 | Clemson (14-1,9-0) | 37 | at | Syracuse | 27 | |||
| 11/21/2015 | Syracuse | 29 | at | North Carolina State (7-6,3-5) | 42 | |||
| 11/28/2015 | Boston College (3-9,0-8) | 17 | at | Syracuse | 20 |
| vs Syracuse | vs Other Opponents | Syracuse compared to OOs | |
| Record: | 8-4 | 74-66 | |
| Points Scored: | 31.00 | 27.32 | -3.68 |
| Points Allowed: | 27.25 | 23.44 | 3.81 |
| Margin: | 3.75 | 3.88 | 0.13 |
| Total Points: | 58.25 | 50.76 | 7.49 |