| 9/5/2015 | Missouri State (1-10) | 7 | at | Memphis | 63 | MVC (1AA) | ||
| 9/12/2015 | Memphis | 55 | at | Kansas (0-12) | 23 | at B12 | ||
| 9/19/2015 | Memphis | 44 | at | Bowling Green (10-4) | 41 | at MAC | ||
| 9/24/2015 | Cincinnati (7-6,4-4) | 46 | at | Memphis | 53 | |||
| 10/2/2015 | Memphis | 24 | at | South Florida (8-5,6-2) | 17 | |||
| 10/17/2015 | Mississippi (10-3) | 24 | at | Memphis | 37 | SEC | ||
| 10/23/2015 | Memphis | 66 | at | Tulsa (6-7,3-5) | 42 | |||
| 10/31/2015 | Tulane (3-9,1-7) | 13 | at | Memphis | 41 | |||
| 11/7/2015 | Navy (11-2,7-1) | 45 | at | Memphis | 20 | |||
| 11/14/2015 | Memphis | 34 | at | Houston (13-1,8-1) | 35 | |||
| 11/21/2015 | Memphis | 12 | at | Temple (10-4,7-2) | 31 | |||
| 11/28/2015 | SMU (2-10,1-7) | 0 | at | Memphis | 63 | |||
| 12/30/2015 | Auburn (7-6) | 31 | vs | Memphis | 10 | Birmingham Bowl (Birmingham AL) | SEC |
| vs Memphis | vs Other Opponents | Memphis compared to OOs | |
| Record: | 4-9 | 84-70 | |
| Points Scored: | 27.31 | 31.19 | 3.88 |
| Points Allowed: | 40.15 | 30.28 | 9.87 |
| Margin: | -12.84 | 0.91 | 13.75 |
| Total Points: | 67.46 | 61.47 | 5.99 |