| 9/4/2010 | Weber State Wildcats 20 @ Boston College 38 | |
| 9/11/2010 | Kent State Golden Flashes 13 @ Boston College 26 | |
| 9/25/2010 | Virginia Tech Hokies 19 @ Boston College 0 | † |
| 10/2/2010 | Notre Dame Fighting Irish 31 @ Boston College 13 | |
| 10/9/2010 | Boston College 17 @ North Carolina State Wolfpack 44 | † |
| 10/16/2010 | Boston College 19 @ Florida State Seminoles 24 | † |
| 10/23/2010 | Maryland Terrapins 24 @ Boston College 21 | † |
| 10/30/2010 | Clemson Tigers 10 @ Boston College 16 | † |
| 11/6/2010 | Boston College 23 @ Wake Forest Demon Deacons 13 | † |
| 11/13/2010 | Boston College 21 @ Duke Blue Devils 16 | † |
| 11/20/2010 | Virginia Cavaliers 13 @ Boston College 17 | † |
| 11/27/2010 | Boston College 16 @ Syracuse Orangemen 7 | |
| 1/9/2011 | Nevada Wolf Pack 20 vs Boston College 13 (San Francisco - Kraft Fight Hunger Bowl) |