| 9/6/2010 | Navy Midshipmen 14 vs Maryland 17 (Baltimore MD) | |
| 9/11/2010 | Morgan State Golden Bears 3 @ Maryland 62 | |
| 9/18/2010 | Maryland 17 @ West Virginia Mountaineers 31 | |
| 9/25/2010 | Florida Intl Golden Panthers 28 @ Maryland 42 | |
| 10/2/2010 | Duke Blue Devils 16 @ Maryland 21 | † |
| 10/16/2010 | Maryland 7 @ Clemson Tigers 31 | † |
| 10/23/2010 | Maryland 24 @ Boston College Eagles 21 | † |
| 10/30/2010 | Wake Forest Demon Deacons 14 @ Maryland 62 | † |
| 11/6/2010 | Maryland 20 @ Miami-Florida Hurricanes 26 | † |
| 11/13/2010 | Maryland 42 @ Virginia Cavaliers 23 | † |
| 11/20/2010 | Florida State Seminoles 30 @ Maryland 16 | † |
| 11/27/2010 | North Carolina State Wolfpack 31 @ Maryland 38 | † |
| 12/29/2010 | East Carolina Pirates 20 vs Maryland 51 (Washington DC - Military Bowl) |