| 9/4/2010 | Weber State 20 @ Boston College Eagles 38 | |
| 9/11/2010 | Northern Colorado Bears 47 @ Weber State 41 3OT | † |
| 9/18/2010 | Weber State 17 @ Sacramento State Hornets 24 | † |
| 9/25/2010 | UC Davis Aggies 9 @ Weber State 20 | |
| 10/2/2010 | Eastern Washington Eagles 35 @ Weber State 24 | † |
| 10/16/2010 | Weber State 16 @ Idaho State Bengals 13 | † |
| 10/23/2010 | Portland State Vikings 41 @ Weber State 44 | † |
| 10/30/2010 | Montana Grizzlies 21 @ Weber State 30 | † |
| 11/6/2010 | Weber State 10 @ Montana State Bobcats 24 | † |
| 11/13/2010 | Weber State 27 @ Northern Arizona Lumberjacks 26 | † |
| 11/20/2010 | Weber State 21 @ Texas Tech Red Raiders 58 |