| 9/2/2010 | Murray State Racers 10 @ Kent State 41 | |
| 9/11/2010 | Kent State 13 @ Boston College Eagles 26 | |
| 9/18/2010 | Kent State 0 @ Penn State Nittany Lions 24 | |
| 10/2/2010 | Kent State 21 @ Miami-Ohio Redhawks 27 | † |
| 10/9/2010 | Akron Zips 17 @ Kent State 28 | † |
| 10/16/2010 | Kent State 21 @ Toledo Rockets 34 | † |
| 10/23/2010 | Kent State 30 @ Bowling Green Falcons 6 | † |
| 10/30/2010 | Ball State Cardinals 14 @ Kent State 33 | † |
| 11/6/2010 | Temple Owls 28 @ Kent State 10 | † |
| 11/13/2010 | Army Black Knights 45 @ Kent State 28 | |
| 11/20/2010 | Kent State 3 @ Western Michigan Broncos 38 | † |
| 11/26/2010 | Ohio Bobcats 6 @ Kent State 28 | † |