| 9/4/2010 | Illinois Fighting Illini 13 vs Missouri 23 (St Louis MO) | |
| 9/11/2010 | McNeese State Cowboys 6 @ Missouri 50 | |
| 9/18/2010 | San Diego State Aztecs 24 @ Missouri 27 | |
| 9/25/2010 | Miami-Ohio Redhawks 13 @ Missouri 51 | |
| 10/9/2010 | Colorado Buffaloes 0 @ Missouri 26 | † |
| 10/16/2010 | Missouri 30 @ Texas A&M Aggies 9 | † |
| 10/23/2010 | Oklahoma Sooners 27 @ Missouri 36 | † |
| 10/30/2010 | Missouri 17 @ Nebraska Cornhuskers 31 | † |
| 11/6/2010 | Missouri 17 @ Texas Tech Red Raiders 24 | † |
| 11/13/2010 | Kansas State Wildcats 28 @ Missouri 38 | † |
| 11/20/2010 | Missouri 14 @ Iowa State Cyclones 0 | † |
| 11/27/2010 | Missouri 35 vs Kansas Jayhawks 7 (Kansas City MO) | † |
| 12/28/2010 | Missouri 24 vs Iowa Hawkeyes 27 (Phoenix - Insight Bowl) |