| 9/4/2010 | Bowie State Bulldogs 7 @ Morgan State 14 | |
| 9/11/2010 | Morgan State 3 @ Maryland Terrapins 62 | |
| 9/18/2010 | Morgan State 9 @ North Dakota State Bison 35 | |
| 9/25/2010 | Howard Bison 3 vs Morgan State 20 (East Rutherford NJ) | † |
| 10/2/2010 | Bethune-Cookman Wildcats 69 @ Morgan State 32 | † |
| 10/9/2010 | Morgan State 27 @ North Carolina A&T Aggies 14 | † |
| 10/23/2010 | Delaware State Hornets 24 @ Morgan State 34 | † |
| 10/30/2010 | Morgan State 17 @ Florida A&M Rattlers 31 | † |
| 11/6/2010 | Morgan State 25 @ Norfolk State Spartans 37 | † |
| 11/11/2010 | South Carolina State Bulldogs 32 @ Morgan State 10 | † |
| 11/20/2010 | Hampton Pirates 21 @ Morgan State 16 | † |