| 9/10/2022 | North Central | 56 | at | Wabash (7-3) | 12 | at NCA | ||
| 9/17/2022 | North Central | 59 | at | Carthage (3-7,3-6) | 7 | |||
| 9/24/2022 | Elmhurst (0-10,0-9) | 6 | at | North Central | 76 | |||
| 10/1/2022 | Wheaton (8-3,8-1) | 20 | at | North Central | 33 | |||
| 10/8/2022 | North Central | 73 | at | Carroll WI (6-4,5-4) | 0 | |||
| 10/15/2022 | Millikin (4-6,3-6) | 0 | at | North Central | 65 | |||
| 10/22/2022 | North Central | 31 | at | Washington U (8-3,7-2) | 0 | |||
| 10/29/2022 | North Park (1-9,1-8) | 0 | at | North Central | 59 | |||
| 11/5/2022 | North Central | 68 | at | Illinois Wesleyan (6-4,5-4) | 3 | |||
| 11/12/2022 | Augustana IL (5-5,4-5) | 3 | at | North Central | 63 | |||
| 11/19/2022 | Lake Forest (9-2) | 0 | at | North Central | 50 | D3 Championship Round 1 | MidW | |
| 11/26/2022 | Carnegie Mellon (11-1) | 7 | at | North Central | 28 | D3 Playoffs Round 2 | TPAC | |
| 12/3/2022 | Ithaca (12-1) | 7 | at | North Central | 48 | D3 Quarterfinals | LL | |
| 12/10/2022 | Mary Hardin-Baylor (12-2) | 14 | at | North Central | 49 | D3 Semifinal | ASWC | |
| 12/16/2022 | Mount Union (14-1) | 21 | vs | North Central | 28 | D3 Championship - Annapolis MD | OAC |
| vs North Central | vs Other Opponents | North Central compared to OOs | |
| Record: | 0-15 | 106-46 | |
| Points Scored: | 6.67 | 34.21 | 27.54 |
| Points Allowed: | 52.40 | 22.20 | 30.20 |
| Margin: | -45.73 | 12.01 | 57.74 |
| Total Points: | 59.07 | 56.41 | 2.66 |