| 9/3/2022 | Muhlenberg (7-4) | 13 | at | Mary Hardin-Baylor | 62 | Cen | ||
| 9/10/2022 | Mary Hardin-Baylor | 24 | at | Wisconsin-Whitewater (8-3) | 28 | at WIAC | ||
| 9/17/2022 | Southwestern Texas (3-7,2-6) | 14 | at | Mary Hardin-Baylor | 68 | |||
| 9/24/2022 | Mary Hardin-Baylor | 50 | at | Hardin-Simmons (9-2,7-1) | 20 | |||
| 10/1/2022 | Austin (1-9,1-7) | 7 | at | Mary Hardin-Baylor | 38 | |||
| 10/8/2022 | Mary Hardin-Baylor | 24 | at | East Texas Baptist (5-5,4-4) | 7 | |||
| 10/15/2022 | Mary Hardin-Baylor | 45 | at | Texas Lutheran (4-6,3-5) | 16 | |||
| 10/22/2022 | Sul Ross State (4-6,4-4) | 14 | at | Mary Hardin-Baylor | 45 | |||
| 11/5/2022 | Mary Hardin-Baylor | 27 | at | Howard Payne (7-3,6-2) | 24 | |||
| 11/12/2022 | McMurry (1-9,1-7) | 3 | at | Mary Hardin-Baylor | 62 | |||
| 11/19/2022 | Huntingdon AL (9-2) | 0 | at | Mary Hardin-Baylor | 54 | D3 Championship Round 1 | USASC | |
| 11/26/2022 | Mary Hardin-Baylor | 24 | at | Trinity TX (11-1) | 17 | D3 Playoffs Round 2 | at SAA | |
| 12/3/2022 | Bethel MN (10-3) | 28 | at | Mary Hardin-Baylor | 41 | D3 Quarterfinals | MIA | |
| 12/10/2022 | Mary Hardin-Baylor | 14 | at | North Central (15-0) | 49 | D3 Semifinal | at CCIW |
| vs Mary Hardin-Baylor | vs Other Opponents | Mary Hardin-Baylor compared to OOs | |
| Record: | 2-12 | 92-48 | |
| Points Scored: | 17.14 | 33.04 | 15.90 |
| Points Allowed: | 41.29 | 21.83 | 19.46 |
| Margin: | -24.15 | 11.21 | 35.36 |
| Total Points: | 58.43 | 54.87 | 3.56 |