| 9/3/2022 | Defiance (3-7) | 0 | at | Mount Union | 65 | HCA | ||
| 9/17/2022 | Marietta (6-4,5-4) | 7 | at | Mount Union | 55 | |||
| 9/24/2022 | Mount Union | 59 | at | Muskingum (5-5,4-5) | 0 | |||
| 10/1/2022 | Mount Union | 45 | at | Ohio Northern (3-7,3-6) | 0 | |||
| 10/8/2022 | Heidelberg (7-3,6-3) | 6 | at | Mount Union | 28 | |||
| 10/15/2022 | Mount Union | 49 | at | Capital (0-10,0-9) | 14 | |||
| 10/22/2022 | Wilmington (3-7,2-7) | 3 | at | Mount Union | 63 | |||
| 10/29/2022 | Mount Union | 59 | at | Otterbein (2-8,1-8) | 0 | |||
| 11/5/2022 | John Carroll (8-2,8-1) | 28 | at | Mount Union | 34 | |||
| 11/12/2022 | Mount Union | 23 | at | Baldwin-Wallace (7-3,7-2) | 21 | |||
| 11/19/2022 | Salisbury (9-2) | 0 | at | Mount Union | 51 | D3 Championship Round 1 | NJAC | |
| 11/26/2022 | Utica (10-2) | 7 | at | Mount Union | 45 | D3 Playoffs Round 2 | E8 | |
| 12/3/2022 | Mount Union | 22 | at | Delaware Valley (12-1) | 6 | D3 Quarterfinals | at MidAC | |
| 12/10/2022 | Wartburg (13-1) | 31 | at | Mount Union | 34 | D3 Semifinal | ARC | |
| 12/16/2022 | Mount Union | 21 | vs | North Central (15-0) | 28 | D3 Championship - Annapolis MD | vs CCIW |
| vs Mount Union | vs Other Opponents | Mount Union compared to OOs | |
| Record: | 1-14 | 102-48 | |
| Points Scored: | 10.07 | 31.37 | 21.30 |
| Points Allowed: | 43.53 | 20.03 | 23.50 |
| Margin: | -33.46 | 11.34 | 44.80 |
| Total Points: | 53.60 | 51.40 | 2.20 |