| 9/3/2022 | Wisconsin Lutheran (4-6) | 7 | at | Lake Forest | 42 | NAC | ||
| 9/10/2022 | Lake Forest | 55 | at | Lawrence (0-10,0-9) | 0 | |||
| 9/17/2022 | Knox (5-5,4-5) | 14 | at | Lake Forest | 48 | |||
| 10/1/2022 | Lake Forest | 41 | at | Cornell IA (3-7,3-6) | 10 | |||
| 10/8/2022 | Illinois College (5-4,4-4) | 7 | at | Lake Forest | 40 | |||
| 10/15/2022 | Ripon (9-1,8-1) | 16 | at | Lake Forest | 14 | |||
| 10/22/2022 | Grinnell (2-6,2-6) | 0 | at | Lake Forest | 49 | |||
| 10/29/2022 | Monmouth IL (9-2,8-1) | 14 | at | Lake Forest | 31 | |||
| 11/5/2022 | Lake Forest | 36 | at | Beloit (1-9,1-8) | 3 | |||
| 11/12/2022 | Lake Forest | 13 | at | Chicago (7-3,6-3) | 7 | |||
| 11/19/2022 | Lake Forest | 0 | at | North Central (15-0) | 50 | D3 Championship Round 1 | at CCIW |
| vs Lake Forest | vs Other Opponents | Lake Forest compared to OOs | |
| Record: | 2-9 | 58-44 | |
| Points Scored: | 11.64 | 30.07 | 18.43 |
| Points Allowed: | 33.55 | 24.99 | 8.56 |
| Margin: | -21.91 | 5.08 | 26.99 |
| Total Points: | 45.19 | 55.06 | -9.87 |