| 9/3/2022 | Manchester (1-9) | 23 | at | North Park | 14 | HCA | ||
| 9/17/2022 | North Park | 0 | at | Carroll WI (6-4,5-4) | 42 | |||
| 9/24/2022 | North Park | 21 | at | Millikin (4-6,3-6) | 23 | |||
| 10/1/2022 | Washington U (8-3,7-2) | 56 | at | North Park | 21 | |||
| 10/8/2022 | Carthage (3-7,3-6) | 33 | at | North Park | 14 | |||
| 10/15/2022 | North Park | 34 | at | Illinois Wesleyan (6-4,5-4) | 43 | |||
| 10/22/2022 | Augustana IL (5-5,4-5) | 56 | at | North Park | 34 | |||
| 10/29/2022 | North Park | 0 | at | North Central (15-0,9-0) | 59 | |||
| 11/5/2022 | Elmhurst (0-10,0-9) | 20 | at | North Park | 23 | |||
| 11/12/2022 | North Park | 14 | at | Wheaton (8-3,8-1) | 54 |
| vs North Park | vs Other Opponents | North Park compared to OOs | |
| Record: | 9-1 | 47-50 | |
| Points Scored: | 40.90 | 29.59 | -11.31 |
| Points Allowed: | 17.50 | 29.48 | -11.98 |
| Margin: | 23.40 | 0.11 | -23.29 |
| Total Points: | 58.40 | 59.07 | -0.67 |