| 9/4/2010 | Wisconsin 41 @ UNLV Rebels 21 | |
| 9/11/2010 | San Jose State Spartans 14 @ Wisconsin 27 | |
| 9/18/2010 | Arizona State Sun Devils 19 @ Wisconsin 20 | |
| 9/25/2010 | Austin Peay Governers 3 @ Wisconsin 70 | |
| 10/2/2010 | Wisconsin 24 @ Michigan State Spartans 34 | † |
| 10/9/2010 | Minnesota Golden Gophers 23 @ Wisconsin 41 | † |
| 10/16/2010 | Ohio State Buckeyes 18 @ Wisconsin 31 | † |
| 10/23/2010 | Wisconsin 31 @ Iowa Hawkeyes 30 | † |
| 11/6/2010 | Wisconsin 34 @ Purdue Boilermakers 13 | † |
| 11/13/2010 | Indiana Hoosiers 20 @ Wisconsin 83 | † |
| 11/20/2010 | Wisconsin 48 @ Michigan Wolverines 28 | † |
| 11/27/2010 | Northwestern Wildcats 23 @ Wisconsin 70 | † |
| 1/1/2011 | Wisconsin 19 vs TCU Horned Frogs 21 (Pasadena - Rose Bowl) |