| 9/4/2010 | Portland State Vikings 9 @ Arizona State 54 | |
| 9/11/2010 | Northern Arizona Lumberjacks 20 @ Arizona State 41 | |
| 9/18/2010 | Arizona State 19 @ Wisconsin Badgers 20 | |
| 9/25/2010 | Oregon Ducks 42 @ Arizona State 31 | † |
| 10/2/2010 | Arizona State 28 @ Oregon State Beavers 31 | † |
| 10/9/2010 | Arizona State 24 @ Washington Huskies 14 | † |
| 10/23/2010 | Arizona State 17 @ California Golden Bears 50 | † |
| 10/30/2010 | Washington State Cougars 0 @ Arizona State 42 | † |
| 11/6/2010 | Arizona State 33 @ Southern California Trojans 34 | † |
| 11/13/2010 | Stanford Cardinal 17 @ Arizona State 13 | † |
| 11/26/2010 | UCLA Bruins 34 @ Arizona State 55 | † |
| 12/2/2010 | Arizona State 30 @ Arizona Wildcats 29 2OT | † |