| 9/4/2010 | Hampden-Sydney @ Averett | |
| 9/4/2010 | Wesley @ Christopher Newport | |
| 9/4/2010 | Emory & Henry @ Ferrum | |
| 9/4/2010 | Greensboro @ Guilford | |
| 9/4/2010 | Maryville @ Huntingdon AL | |
| 9/4/2010 | Randolph-Macon @ Methodist | |
| 9/4/2010 | North Carolina Wesleyan @ Salisbury | |
| 9/4/2010 | Catholic @ Shenandoah | |
| 9/11/2010 | Shenandoah @ Bridgewater VA | |
| 9/11/2010 | Emory & Henry @ Greensboro | |
| 9/11/2010 | Methodist @ Guilford | |
| 9/11/2010 | North Carolina Wesleyan @ Hampden-Sydney | |
| 9/11/2010 | Centre @ Maryville | |
| 9/11/2010 | Christopher Newport @ Salisbury | |
| 9/18/2010 | Greensboro @ Apprentice | |
| 9/18/2010 | Guilford @ Averett | |
| 9/18/2010 | Southern Virginia @ Ferrum | |
| 9/18/2010 | Christopher Newport @ Frostburg State | |
| 9/18/2010 | LaGrange @ Maryville | |
| 9/18/2010 | Shenandoah @ Randolph-Macon | |
| 9/25/2010 | Ferrum @ Bridgewater VA | |
| 9/25/2010 | Methodist @ Emory & Henry | |
| 9/25/2010 | LaGrange @ North Carolina Wesleyan | |
| 9/25/2010 | Averett @ Washington and Lee | |
| 10/2/2010 | Greensboro @ Averett | † |
| 10/2/2010 | North Carolina Wesleyan @ Ferrum | † |
| 10/2/2010 | Maryville @ Methodist | † |
| 10/2/2010 | Christopher Newport @ Shenandoah | † |
| 10/9/2010 | Averett @ Christopher Newport | † |
| 10/9/2010 | Shenandoah @ Maryville | † |
| 10/9/2010 | Ferrum @ Methodist | † |
| 10/9/2010 | Greensboro @ North Carolina Wesleyan | † |
| 10/16/2010 | Maryville @ Averett | † |
| 10/16/2010 | Ferrum @ Greensboro | † |
| 10/16/2010 | Christopher Newport @ North Carolina Wesleyan | † |
| 10/16/2010 | Methodist @ Shenandoah | † |
| 10/23/2010 | Greensboro @ Christopher Newport | † |
| 10/23/2010 | Shenandoah @ Ferrum | † |
| 10/23/2010 | North Carolina Wesleyan @ Maryville | † |
| 10/23/2010 | Averett @ Methodist | † |
| 10/30/2010 | Ferrum @ Christopher Newport | † |
| 10/30/2010 | Maryville @ Greensboro | † |
| 10/30/2010 | Methodist @ North Carolina Wesleyan | † |
| 10/30/2010 | Averett @ Shenandoah | † |
| 11/6/2010 | Ferrum @ Averett | † |
| 11/6/2010 | Christopher Newport @ Maryville | † |
| 11/6/2010 | Greensboro @ Methodist | † |
| 11/6/2010 | North Carolina Wesleyan @ Shenandoah | † |
| 11/13/2010 | Methodist @ Christopher Newport | † |
| 11/13/2010 | Maryville @ Ferrum | † |
| 11/13/2010 | Shenandoah @ Greensboro | † |
| 11/13/2010 | Averett @ North Carolina Wesleyan | † |