| 9/11/2010 | Apprentice 32 @ Catholic Cardinals 42 | |
| 9/18/2010 | Greensboro Pride 7 @ Apprentice 9 | |
| 9/25/2010 | Fairleigh Dickinson-Florham Devils 28 @ Apprentice 14 | |
| 10/2/2010 | Salisbury Seagulls 31 @ Apprentice 7 | † |
| 10/9/2010 | Apprentice 7 @ Wesley Wolverines 64 | † |
| 10/23/2010 | Apprentice 20 @ Southern Virginia Knights 18 | |
| 10/30/2010 | Apprentice 14 @ LaGrange Panthers 21 | |
| 11/6/2010 | Apprentice 21 @ Frostburg State Bobcats 25 | † |
| 11/13/2010 | Webber International Warriors 40 @ Apprentice 7 |