| 9/4/2010 | Ark Pine Bluff Golden Lions 10 @ UTEP 31 | |
| 9/10/2010 | UTEP 24 @ Houston Cougars 54 | † |
| 9/18/2010 | New Mexico State Aggies 10 @ UTEP 42 | |
| 9/25/2010 | Memphis Tigers 13 @ UTEP 16 | † |
| 10/2/2010 | UTEP 38 @ New Mexico Lobos 20 | |
| 10/9/2010 | Rice Owls 24 @ UTEP 44 | † |
| 10/16/2010 | UTEP 6 @ UAB Blazers 21 | † |
| 10/23/2010 | Tulane Green Wave 34 @ UTEP 24 | † |
| 10/30/2010 | UTEP 12 @ Marshall Thundering Herd 16 | † |
| 11/6/2010 | SMU Mustangs 14 @ UTEP 28 | † |
| 11/13/2010 | UTEP 21 @ Arkansas Razorbacks 58 | |
| 11/20/2010 | UTEP 28 @ Tulsa Golden Hurricane 31 | † |
| 12/18/2010 | BYU Cougars 52 vs UTEP 24 (Albuquerque - New Mexico Bowl) |