| 9/4/2010 | Ark Pine Bluff 10 @ UTEP Miners 31 | |
| 9/11/2010 | Ark Pine Bluff 31 @ Alabama State Hornets 38 | † |
| 9/25/2010 | Clark Atlanta Panthers 19 vs Ark Pine Bluff 35 (St Louis MO) | |
| 10/2/2010 | Ark Pine Bluff 41 @ Southern Jaquars 23 | † |
| 10/7/2010 | Prairie View Panthers 21 @ Ark Pine Bluff 6 | † |
| 10/16/2010 | Alabama A&M Bulldogs 14 @ Ark Pine Bluff 21 | † |
| 10/21/2010 | Ark Pine Bluff 39 @ Alcorn State Braves 35 | † |
| 10/30/2010 | Grambling Tigers 35 vs Ark Pine Bluff 25 (Little Rock AR) | † |
| 11/6/2010 | Mississippi Valley State Delta Devils 20 @ Ark Pine Bluff 49 | † |
| 11/13/2010 | Jackson State Tigers 52 @ Ark Pine Bluff 30 | † |
| 11/20/2010 | Ark Pine Bluff 13 @ Texas Southern Tigers 20 | † |