| 9/4/2010 | Washington Huskies 17 @ BYU 23 | |
| 9/11/2010 | BYU 14 @ Air Force Falcons 35 | † |
| 9/18/2010 | BYU 10 @ Florida State Seminoles 34 | |
| 9/25/2010 | Nevada Wolf Pack 27 @ BYU 13 | |
| 10/1/2010 | BYU 16 @ Utah State Aggies 31 | |
| 10/9/2010 | San Diego State Aztecs 21 @ BYU 24 | † |
| 10/16/2010 | BYU 3 @ TCU Horned Frogs 31 | † |
| 10/23/2010 | Wyoming Cowboys 20 @ BYU 25 | † |
| 11/6/2010 | UNLV Rebels 7 @ BYU 55 | † |
| 11/13/2010 | BYU 49 @ Colorado State Rams 10 | † |
| 11/20/2010 | New Mexico Lobos 7 @ BYU 40 | † |
| 11/27/2010 | BYU 16 @ Utah Utes 17 | † |
| 12/18/2010 | BYU 52 vs UTEP Miners 24 (Albuquerque - New Mexico Bowl) |