| 9/3/2022 | Southwest Baptist | 41 | at | Texas-Permian Basin (5-6) | 17 | at LSC | ||
| 9/10/2022 | West Florida (12-2) | 49 | at | Southwest Baptist | 10 | GSC | ||
| 9/17/2022 | Southwest Baptist | 35 | at | Findlay (7-4) | 52 | at GMAC | ||
| 9/24/2022 | Lake Erie (3-8) | 31 | at | Southwest Baptist | 52 | GMAC | ||
| 10/1/2022 | Southwest Baptist | 17 | at | Indianapolis (9-2,6-0) | 44 | |||
| 10/8/2022 | William Jewell (2-9,1-5) | 21 | at | Southwest Baptist | 44 | |||
| 10/15/2022 | Southwest Baptist | 20 | at | Truman State (9-2,5-1) | 25 | |||
| 10/22/2022 | Southwest Baptist | 10 | at | Tarleton State (6-5) | 24 | at WAC | ||
| 10/29/2022 | Southwest Baptist | 49 | at | McKendree (5-6,2-4) | 31 | |||
| 11/5/2022 | Quincy (4-7,1-5) | 24 | at | Southwest Baptist | 42 | |||
| 11/12/2022 | Southwest Baptist | 24 | at | Missouri S&T (3-7,2-4) | 17 |
| vs Southwest Baptist | vs Other Opponents | Southwest Baptist compared to OOs | |
| Record: | 5-6 | 60-52 | |
| Points Scored: | 30.45 | 29.52 | -0.93 |
| Points Allowed: | 31.27 | 28.63 | 2.64 |
| Margin: | -0.82 | 0.89 | 1.71 |
| Total Points: | 61.72 | 58.15 | 3.57 |