| 9/1/2022 | Alabama A&M | 0 | at | UAB (7-6) | 59 | at CUSA | ||
| 9/10/2022 | Alabama A&M | 17 | at | Troy (12-2) | 38 | at SBC | ||
| 9/17/2022 | Austin Peay (7-4) | 28 | at | Alabama A&M | 3 | ASUN | ||
| 9/24/2022 | Alabama A&M | 25 | at | Florida A&M (9-2,7-1) | 38 | |||
| 10/1/2022 | Bethune-Cookman (2-9,2-6) | 27 | at | Alabama A&M | 35 | |||
| 10/8/2022 | Grambling (3-8,2-7) | 31 | at | Alabama A&M | 37 | OT | ||
| 10/16/2022 | Alabama A&M | 34 | at | Ark Pine Bluff (3-8,1-7) | 31 | |||
| 10/29/2022 | Alabama State (6-5,4-4) | 24 | vs | Alabama A&M | 17 | Birmingham AL | ||
| 11/3/2022 | Alabama A&M | 20 | at | Mississippi Valley State (2-9,2-6) | 30 | |||
| 11/12/2022 | Alabama A&M | 13 | vs | Jackson State (12-1,10-0) | 27 | Mobile AL | ||
| 11/19/2022 | Texas Southern (5-6,4-4) | 20 | at | Alabama A&M | 24 |
| vs Alabama A&M | vs Other Opponents | Alabama A&M compared to OOs | |
| Record: | 7-4 | 61-56 | |
| Points Scored: | 32.09 | 25.05 | -7.04 |
| Points Allowed: | 20.45 | 25.82 | -5.37 |
| Margin: | 11.64 | -0.77 | -12.41 |
| Total Points: | 52.54 | 50.87 | 1.67 |