| 8/27/2022 | Florida A&M | 24 | at | North Carolina (9-5) | 56 | at ACC | ||
| 9/4/2022 | Florida A&M | 3 | vs | Jackson State (12-1,10-0) | 59 | Miami Gardens FL | ||
| 9/10/2022 | Albany State GA (7-3) | 13 | at | Florida A&M | 23 | SIAC (D2) | ||
| 9/24/2022 | Alabama A&M (4-7,4-4) | 25 | at | Florida A&M | 38 | |||
| 10/1/2022 | Mississippi Valley State (2-9,2-6) | 7 | at | Florida A&M | 34 | |||
| 10/8/2022 | Florida A&M | 20 | at | South Carolina State (3-8) | 14 | at MEAC | ||
| 10/15/2022 | Florida A&M | 20 | at | Grambling (3-8,2-7) | 16 | |||
| 10/29/2022 | Ark Pine Bluff (3-8,1-7) | 6 | at | Florida A&M | 27 | |||
| 11/5/2022 | Southern (7-5,5-4) | 16 | at | Florida A&M | 30 | |||
| 11/12/2022 | Florida A&M | 21 | at | Alabama State (6-5,4-4) | 14 | |||
| 11/19/2022 | Florida A&M | 41 | vs | Bethune-Cookman (2-9,2-6) | 20 | Orlando FL |
| vs Florida A&M | vs Other Opponents | Florida A&M compared to OOs | |
| Record: | 2-9 | 56-59 | |
| Points Scored: | 22.36 | 26.17 | 3.81 |
| Points Allowed: | 25.55 | 27.61 | -2.06 |
| Margin: | -3.19 | -1.44 | 1.75 |
| Total Points: | 47.91 | 53.78 | -5.87 |