| 9/1/2022 | Alabama A&M (4-7) | 0 | at | UAB | 59 | SWAC (1AA) | ||
| 9/10/2022 | UAB | 14 | at | Liberty (8-5) | 21 | at Ind | ||
| 9/17/2022 | Georgia Southern (6-7) | 21 | at | UAB | 35 | SBC | ||
| 10/1/2022 | UAB | 24 | at | Rice (5-8,3-5) | 28 | |||
| 10/8/2022 | Middle Tenn State (8-5,4-4) | 14 | at | UAB | 41 | |||
| 10/15/2022 | UNC-Charlotte (3-9,2-6) | 20 | at | UAB | 34 | |||
| 10/21/2022 | UAB | 17 | at | Western Kentucky (9-5,6-2) | 20 | |||
| 10/29/2022 | UAB | 17 | at | Florida Atlantic (5-7,4-4) | 24 | |||
| 11/5/2022 | Texas-San Antonio (11-3,9-0) | 44 | at | UAB | 38 | 2OT | ||
| 11/12/2022 | North Texas (7-7,6-3) | 21 | at | UAB | 41 | |||
| 11/19/2022 | UAB | 10 | at | LSU (10-4) | 41 | at SEC | ||
| 11/26/2022 | UAB | 37 | at | Louisiana Tech (3-9,2-6) | 27 | |||
| 12/16/2022 | Miami-Ohio (6-7) | 20 | vs | UAB | 24 | Nassau BA | MAC |
| vs UAB | vs Other Opponents | UAB compared to OOs | |
| Record: | 6-7 | 79-76 | |
| Points Scored: | 23.15 | 30.01 | 6.86 |
| Points Allowed: | 30.08 | 28.95 | 1.13 |
| Margin: | -6.93 | 1.06 | 7.99 |
| Total Points: | 53.23 | 58.96 | -5.73 |