| 9/3/2022 | Troy | 10 | at | Mississippi (8-5) | 28 | at SEC | ||
| 9/10/2022 | Alabama A&M (4-7) | 17 | at | Troy | 38 | SWAC (1AA) | ||
| 9/17/2022 | Troy | 28 | at | Appalachian State (6-6,3-5) | 32 | |||
| 9/24/2022 | Marshall (9-4,5-3) | 7 | at | Troy | 16 | |||
| 10/1/2022 | Troy | 34 | at | Western Kentucky (9-5) | 27 | at CUSA | ||
| 10/8/2022 | Southern Miss (7-6,4-4) | 10 | at | Troy | 27 | |||
| 10/15/2022 | Texas State (4-8,2-6) | 14 | at | Troy | 17 | |||
| 10/20/2022 | Troy | 10 | at | South Alabama (10-3,7-1) | 6 | |||
| 11/5/2022 | Troy | 23 | at | UL Lafayette (6-7,4-4) | 17 | |||
| 11/12/2022 | Army (6-6) | 9 | at | Troy | 10 | Ind | ||
| 11/19/2022 | UL Monroe (4-8,3-5) | 16 | at | Troy | 34 | |||
| 11/26/2022 | Troy | 48 | at | Arkansas State (3-9,1-7) | 19 | |||
| 12/3/2022 | Coastal Carolina (9-4,6-3) | 26 | at | Troy | 45 | SBC Championship | ||
| 12/16/2022 | Texas-San Antonio (11-3) | 12 | vs | Troy | 18 | Orlando FL | CUSA |
| vs Troy | vs Other Opponents | Troy compared to OOs | |
| Record: | 2-12 | 94-69 | |
| Points Scored: | 17.14 | 29.44 | 12.30 |
| Points Allowed: | 25.57 | 25.87 | -0.30 |
| Margin: | -8.43 | 3.57 | 12.00 |
| Total Points: | 42.71 | 55.31 | -12.60 |