| 9/3/2022 | UL Monroe | 10 | at | Texas (8-5) | 52 | at B12 | ||
| 9/10/2022 | Nicholls State (3-8) | 7 | at | UL Monroe | 35 | SLC (1AA) | ||
| 9/17/2022 | UL Monroe | 7 | at | Alabama (11-2) | 63 | at SEC | ||
| 9/24/2022 | UL Lafayette (6-7,4-4) | 17 | at | UL Monroe | 21 | |||
| 10/1/2022 | UL Monroe | 28 | at | Arkansas State (3-9,1-7) | 45 | |||
| 10/8/2022 | Coastal Carolina (9-4,6-3) | 28 | at | UL Monroe | 21 | |||
| 10/15/2022 | UL Monroe | 34 | at | South Alabama (10-3,7-1) | 41 | |||
| 10/22/2022 | UL Monroe | 24 | at | Army (6-6) | 48 | at Ind | ||
| 11/5/2022 | Texas State (4-8,2-6) | 30 | at | UL Monroe | 31 | |||
| 11/12/2022 | UL Monroe | 31 | at | Georgia State (4-8,3-5) | 28 | |||
| 11/19/2022 | UL Monroe | 16 | at | Troy (12-2,8-1) | 34 | |||
| 11/26/2022 | Southern Miss (7-6,4-4) | 20 | at | UL Monroe | 10 |
| vs UL Monroe | vs Other Opponents | UL Monroe compared to OOs | |
| Record: | 8-4 | 75-64 | |
| Points Scored: | 34.42 | 27.62 | -6.80 |
| Points Allowed: | 22.33 | 25.24 | -2.91 |
| Margin: | 12.09 | 2.38 | -9.71 |
| Total Points: | 56.75 | 52.86 | 3.89 |