| 9/4/2021 | Lycoming (8-3) | 10 | at | Susquehanna | 44 | MidAC | ||
| 9/11/2021 | Susquehanna | 30 | at | Franklin & Marshall (6-5,5-4) | 28 | 5OT | ||
| 9/18/2021 | Susquehanna | 44 | at | Moravian (3-7,3-6) | 0 | |||
| 9/25/2021 | Dickinson (4-6,4-5) | 14 | at | Susquehanna | 31 | |||
| 10/2/2021 | Susquehanna | 62 | at | Ursinus (7-4,6-3) | 23 | |||
| 10/15/2021 | Gettysburg (1-9,1-8) | 7 | at | Susquehanna | 47 | |||
| 10/23/2021 | McDaniel (2-8,2-7) | 16 | at | Susquehanna | 45 | |||
| 10/30/2021 | Susquehanna | 17 | at | Johns Hopkins (10-2,8-1) | 38 | |||
| 11/6/2021 | Muhlenberg (11-2,8-1) | 52 | at | Susquehanna | 27 | |||
| 11/13/2021 | Susquehanna | 65 | at | Juniata (1-9,1-8) | 0 | |||
| 11/20/2021 | Widener (7-4) | 21 | at | Susquehanna | 49 | MidAC |
| vs Susquehanna | vs Other Opponents | Susquehanna compared to OOs | |
| Record: | 2-9 | 58-50 | |
| Points Scored: | 19.00 | 24.65 | 5.65 |
| Points Allowed: | 41.91 | 22.31 | 19.60 |
| Margin: | -22.91 | 2.34 | 25.25 |
| Total Points: | 60.91 | 46.96 | 13.95 |