| 9/4/2021 | Moravian | 10 | at | King's (5-5) | 13 | at MidAC | ||
| 9/11/2021 | Moravian | 16 | at | Gettysburg (1-9,1-8) | 13 | OT | ||
| 9/18/2021 | Susquehanna (9-2,7-2) | 44 | at | Moravian | 0 | |||
| 9/25/2021 | Johns Hopkins (10-2,8-1) | 54 | at | Moravian | 6 | |||
| 10/2/2021 | Moravian | 17 | at | Juniata (1-9,1-8) | 24 | |||
| 10/16/2021 | Dickinson (4-6,4-5) | 14 | at | Moravian | 21 | |||
| 10/23/2021 | Ursinus (7-4,6-3) | 34 | at | Moravian | 7 | |||
| 10/30/2021 | Moravian | 37 | at | McDaniel (2-8,2-7) | 31 | OT | ||
| 11/6/2021 | Franklin & Marshall (6-5,5-4) | 14 | at | Moravian | 10 | |||
| 11/13/2021 | Moravian | 0 | at | Muhlenberg (11-2,8-1) | 55 |
| vs Moravian | vs Other Opponents | Moravian compared to OOs | |
| Record: | 7-3 | 49-49 | |
| Points Scored: | 29.60 | 26.28 | -3.32 |
| Points Allowed: | 12.40 | 25.05 | -12.65 |
| Margin: | 17.20 | 1.23 | -15.97 |
| Total Points: | 42.00 | 51.33 | -9.33 |