| 9/4/2010 | Allegheny @ Bethany WV | |
| 9/4/2010 | Geneva @ Frostburg State | |
| 9/4/2010 | Carnegie Mellon @ Grove City | |
| 9/4/2010 | Westminster PA @ Hiram | |
| 9/4/2010 | Bridgewater VA @ St Vincent | |
| 9/4/2010 | Marietta @ Thiel | |
| 9/11/2010 | Washington & Jefferson @ Delaware Valley | |
| 9/11/2010 | St Vincent @ Fairleigh Dickinson-Florham | |
| 9/11/2010 | Albright @ Geneva | |
| 9/11/2010 | Thomas More @ Hanover | |
| 9/11/2010 | Bethany WV @ King's | |
| 9/11/2010 | Grove City @ Lebanon Valley | |
| 9/11/2010 | Westminster PA @ Lycoming | |
| 9/11/2010 | Thiel @ Widener | |
| 9/11/2010 | Waynesburg @ Wilkes | |
| 9/18/2010 | Thomas More @ Geneva | † |
| 9/18/2010 | Waynesburg @ Thiel | † |
| 9/18/2010 | Bethany WV @ Washington & Jefferson | † |
| 9/18/2010 | Grove City @ Westminster PA | † |
| 9/25/2010 | Geneva @ Bethany WV | † |
| 9/25/2010 | Thiel @ St Vincent | † |
| 9/25/2010 | Washington & Jefferson @ Thomas More | † |
| 9/25/2010 | Grove City @ Waynesburg | † |
| 10/2/2010 | Waynesburg @ Bethany WV | † |
| 10/2/2010 | Geneva @ St Vincent | † |
| 10/2/2010 | Thiel @ Thomas More | † |
| 10/2/2010 | Westminster PA @ Washington & Jefferson | † |
| 10/9/2010 | Waynesburg @ Geneva | † |
| 10/9/2010 | Thomas More @ Grove City | † |
| 10/9/2010 | St Vincent @ Washington & Jefferson | † |
| 10/9/2010 | Bethany WV @ Westminster PA | † |
| 10/16/2010 | Geneva @ Grove City | † |
| 10/16/2010 | Bethany WV @ Thiel | † |
| 10/16/2010 | St Vincent @ Thomas More | † |
| 10/16/2010 | Frostburg State @ Washington & Jefferson | |
| 10/16/2010 | Westminster PA @ Waynesburg | † |
| 10/23/2010 | Thomas More @ Bethany WV | † |
| 10/23/2010 | Washington & Jefferson @ Geneva | † |
| 10/23/2010 | Grove City @ St Vincent | † |
| 10/23/2010 | Frostburg State @ Waynesburg | |
| 10/23/2010 | Thiel @ Westminster PA | † |
| 10/30/2010 | Waynesburg @ St Vincent | † |
| 10/30/2010 | Geneva @ Thiel | † |
| 10/30/2010 | Westminster PA @ Thomas More | † |
| 10/30/2010 | Grove City @ Washington & Jefferson | † |
| 11/6/2010 | Bethany WV @ Grove City | † |
| 11/6/2010 | Washington & Jefferson @ Thiel | † |
| 11/6/2010 | Thomas More @ Waynesburg | † |
| 11/6/2010 | St Vincent @ Westminster PA | † |
| 11/13/2010 | St Vincent @ Bethany WV | † |
| 11/13/2010 | Westminster PA @ Geneva | † |
| 11/13/2010 | Thiel @ Grove City | † |
| 11/13/2010 | Mt St Joseph @ Thomas More | |
| 11/13/2010 | Washington & Jefferson @ Waynesburg | † |