| 9/11/2010 | St Vincent Bearcats 23 @ Fairleigh Dickinson-Florham 28 | |
| 9/17/2010 | New Jersey Lions 23 @ Fairleigh Dickinson-Florham 24 1OT | |
| 9/25/2010 | Fairleigh Dickinson-Florham 28 @ Apprentice Ship Builders 14 | |
| 10/2/2010 | Fairleigh Dickinson-Florham 20 @ Widener Pride 35 | † |
| 10/9/2010 | Delaware Valley Aggies 55 @ Fairleigh Dickinson-Florham 14 | † |
| 10/16/2010 | Fairleigh Dickinson-Florham 21 @ Lebanon Valley Flying Dutchmen 33 | † |
| 10/23/2010 | Wilkes Colonels 28 @ Fairleigh Dickinson-Florham 23 | † |
| 10/30/2010 | Albright Lions 41 @ Fairleigh Dickinson-Florham 15 | † |
| 11/6/2010 | Fairleigh Dickinson-Florham 14 @ King's Monarchs 45 | † |
| 11/13/2010 | Lycoming Warriors 17 @ Fairleigh Dickinson-Florham 10 | † |