| 9/3/2022 | Dubuque (6-4) | 13 | at | Marietta | 14 | ARC | ||
| 9/17/2022 | Marietta | 7 | at | Mount Union (14-1,9-0) | 55 | |||
| 9/24/2022 | Marietta | 27 | at | Otterbein (2-8,1-8) | 10 | |||
| 10/1/2022 | Baldwin-Wallace (7-3,7-2) | 33 | at | Marietta | 29 | |||
| 10/8/2022 | Marietta | 10 | at | John Carroll (8-2,8-1) | 45 | |||
| 10/15/2022 | Wilmington (3-7,2-7) | 0 | at | Marietta | 34 | |||
| 10/22/2022 | Marietta | 21 | at | Heidelberg (7-3,6-3) | 29 | |||
| 10/29/2022 | Ohio Northern (3-7,3-6) | 10 | at | Marietta | 27 | |||
| 11/5/2022 | Capital (0-10,0-9) | 14 | at | Marietta | 50 | |||
| 11/12/2022 | Marietta | 38 | at | Muskingum (5-5,4-5) | 23 |
| vs Marietta | vs Other Opponents | Marietta compared to OOs | |
| Record: | 4-6 | 51-44 | |
| Points Scored: | 23.20 | 27.41 | 4.21 |
| Points Allowed: | 25.70 | 23.87 | 1.83 |
| Margin: | -2.50 | 3.54 | 6.04 |
| Total Points: | 48.90 | 51.28 | -2.38 |